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Article
Open AccessAltered plasma protein profiles in genetic FTD – a GENFI study
Plasma biomarkers reflecting the pathology of frontotemporal dementia would add significant value to clinical practice, to the design and implementation of treatment trials as well as our understanding of dise...
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Article
Open AccessA panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study
A detailed understanding of the pathological processes involved in genetic frontotemporal dementia is critical in order to provide the patients with an optimal future treatment. Protein levels in CSF have the ...
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Article
Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset
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Article
Altered perivascular fibroblast activity precedes ALS disease onset
Apart from well-defined factors in neuronal cells1, only a few reports consider that the variability of sporadic amyotrophic lateral sclerosis (ALS) progression can depend on less-defined contributions from glia2
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Article
Open AccessAssociation of CSF proteins with tau and amyloid β levels in asymptomatic 70-year-olds
Increased knowledge of the evolution of molecular changes in neurodegenerative disorders such as Alzheimer’s disease (AD) is important for the understanding of disease pathophysiology and also crucial to be ab...
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Article
Open AccessAltered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers
The clinical presentations of frontotemporal dementia (FTD) are diverse and overlap with other neurological disorders. There are, as of today, no biomarkers in clinical practice for diagnosing the disorders. H...
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Protocol
Array-Based Profiling of Proteins and Autoantibody Repertoires in CSF
Protein profiling enabled through affinity proteomics represents a powerful strategy for analysis of complex samples such as human body fluids. Cerebrospinal fluid (CSF) is the proximal fluid of the central ne...
