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Protocol
Array-Based Multiplex and High-Throughput Serology Assays
The detection of antibody responses using serological tests provides means to diagnose infections, follow disease transmission, and monitor vaccination responses. The coronavirus disease 2019 (COVID-19) pandem...
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Article
Open AccessSARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthca...
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Protocol
Array-Based Profiling of Proteins and Autoantibody Repertoires in CSF
Protein profiling enabled through affinity proteomics represents a powerful strategy for analysis of complex samples such as human body fluids. Cerebrospinal fluid (CSF) is the proximal fluid of the central ne...
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Article
Open AccessILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
Dogs can spontaneously develop complex systemic autoimmune disorders, with similarities to human autoimmune disease. Autoantibodies directed at self-antigens are a key feature of these autoimmune diseases. Her...
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Protocol
High-Density Antigen Microarrays for the Assessment of Antibody Selectivity and Off-Target Binding
With the increasing availability of collections of antibodies, their evaluation in terms of binding selectivity becomes an important but challenging task. Planar antigen microarrays are very suitable tools to ...
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Protocol
High-Density Serum/Plasma Reverse Phase Protein Arrays
In-depth exploration and characterization of human serum and plasma proteomes is an attractive strategy for the identification of potential prognostic or diagnostic biomarkers. The possibility of analyzing lar...