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Article
Open AccessOsteogenic Differentiation of Human Mesenchymal Stem cells in a 3D Woven Scaffold
Fiber-based scaffolds produced by textile manufacturing technology offer versatile materials for tissue engineering applications since a wide range of crucial scaffold parameters, including porosity, pore size...
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Article
Open AccessThe interplay of matrix metalloproteinase-8, transforming growth factor-β1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma
Matrix metalloproteinase-8 (MMP-8) has oncosuppressive properties in various cancers. We attempted to assess MMP-8 function in oral tongue squamous cell carcinoma (OTSCC).
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Article
Open AccessTenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups
Oral tongue squamous cell carcinoma (OTSCC) metastasises early, especially to regional lymph nodes. There is an ongoing debate on which early stage (T1-T2N0) patients should be treated with elective neck disse...
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Article
Open AccessRheumatoid arthritis antigens homocitrulline and citrulline are generated by local myeloperoxidase and peptidyl arginine deiminases 2, 3 and 4 in rheumatoid nodule and synovial tissue
Seropositive rheumatoid arthritis (RA) is characterized by autoantibodies binding to citrullinated and homocitrullinated proteins. We wanted to study the expression patterns of these disease-associated protein...
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Article
Open AccessSeparate and overlap** specificities in rheumatoid arthritis antibodies binding to citrulline- and homocitrulline-containing peptides related to type I and II collagen telopeptides
Our objective was to find out if there are antibodies binding to homocitrulline-containing type I and II collagen carboxyterminal telopeptides in sera of patients with rheumatoid arthritis (RA), and if these a...
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Article
Open AccessDifferent amounts of protein-bound citrulline and homocitrulline in foot joint tissues of a patient with anti-citrullinated protein antibody positive erosive rheumatoid arthritis
Antibodies binding to citrullinated proteins are a frequent finding in rheumatoid arthritis patients and may precede the onset of clinical symptoms several years. The antibodies are a predisposing factor for b...
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Article
Open AccessDescription of A/C gene mutation related dilated cardiomyopathy with gadolinium- enhanced magnetic resonance imaging
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Article
Open AccessVariability in the precursor proteins of collagen I and III in different stages of COPD
Levels of precursor proteins of collagen I and III are increased in fibrotic pulmonary diseases. This study determined whether the expression of precursors of type I and III collagen proteins would be increase...
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Article
Open AccessMarkers of collagen synthesis and degradation are increased in serum in severe sepsis: a longitudinal study of 44 patients
Sepsis-related multiple organ dysfunction is a common cause of death in the intensive care unit. The effect of sepsis on markers of tissue repair is only partly understood. The aim of this study was to measure...
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Article
Markers of Type I and Type III Collagen Turnover, Insulin-Like Growth Factors, and Their Binding Proteins in Cord Plasma of Small Premature Infants: Relationships with Fetal Growth, Gestational Age, Preeclampsia, and Antenatal Glucocorticoid Treatment
Disorders affecting fetal growth are commonly associated with premature birth. IGFs and their binding proteins (IGFBPs) are potent regulators of fetal growth. In vitro evidence suggests that they regulate collage...
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Collagen turnover and intrauterine growth in small preterm infants
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Markers of Collagen Turnover and Intrauterine Growth in Small Preterm Infants
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Prognostic Value of Serum Hyaluronic Acid and Type I and III Procollagen Propeptides in Extrahepatic Biliary Atresia
Although portoenterostomy has greatly improved the prognosis of extrahepatic biliary atresia (EHBA), 10-20% of patients still die before 5 y of age, and the only treatment option is liver transplantation (LT)....
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Article
Clinical Characteristics and Circulating Collagen and Laminin Metabolites in Insulin-Dependent Diabetic Children with Joint and Skin Manifestations
ABSTRACT: One hundred seventy-four children and adolescents with insulin-dependent diabetes mellitus were examined for joint contractures and skin manifestations in their hands. Joint contractures were found i...
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Serum Concentrations of the Type I and III Procollagen Propeptides as Biochemical Markers of Growth Velocity in Healthy Infants and Children and in Children with Growth Disorders
ABSTRACT: The reproducibility and specificity of a new, rapid, simple RIA for measuring the concentration of the soluble carboxypropeptide of type I procollagen (PICP) in serum was confirmed. Serum PICP was de...
