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Article
Open AccessCombining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard tumor−node−metastasis prognosis classification. Therefore, definin...
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Article
Evaluation of the budding and depth of invasion (BD) model in oral tongue cancer biopsies
It is of great clinical importance to identify simple prognostic markers from preoperative biopsies that could guide treatment planning. Here, we compared tumor budding (B), depth of invasion (D), and the comb...
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Article
Open AccessTenascin-C and fibronectin expression divide early stage tongue cancer into low- and high-risk groups
Oral tongue squamous cell carcinoma (OTSCC) metastasises early, especially to regional lymph nodes. There is an ongoing debate on which early stage (T1-T2N0) patients should be treated with elective neck disse...
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Article
Open AccessA novel human leiomyoma tissue derived matrix for cell culture studies
The composition of the matrix molecules is important in in vitro cell culture experiments of e.g. human cancer invasion and vessel formation. Currently, the mouse Engelbreth-Holm-Swarm (EHS) sarcoma -derived prod...
