39 Result(s)
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Article
Open AccessExploring the tradeoff between data privacy and utility with a clinical data analysis use case
Securing adequate data privacy is critical for the productive utilization of data. De-identification, involving masking or replacing specific values in a dataset, could damage the dataset’s utility. However, f...
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Open AccessResistant hypertension: consensus document from the Korean society of hypertension
Although reports vary, the prevalence of true resistant hypertension and apparent treatment-resistant hypertension (aTRH) has been reported to be 10.3% and 14.7%, respectively. As there is a rapid increase in ...
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Article
Open AccessStatement on chronotherapy for the treatment of hypertension: consensus document from the Korean society of hypertension
Nocturnal blood pressure (BP) has been shown to have a significant predictive value for cardiovascular disease. In some cases, it has a superior predictive value for future cardiovascular outcomes than daytime...
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Open AccessClinical and life style factors related to the nighttime blood pressure, nighttime dip** and their phenotypes in Korean hypertensive patients
Non-dip** or reverse dip** patterns are known to be associated with adverse cardiovascular prognosis among the general population and clinical cohort. Few large sized studies have explored factors includin...
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Development and Application of an Active Pharmacovigilance Framework Based on Electronic Healthcare Records from Multiple Centers in Korea
With the availability of retrospective pharmacovigilance data, the common data model (CDM) has been identified as an efficient approach towards anonymized multicenter analysis; however, the establishment of a ...
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Article
Open AccessThe 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension
Hypertension is the leading cause of death in human being, which shows high prevalence and associated complications that increase the mortality and morbidity. Controlling blood pressure (BP) is very important ...
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Open AccessHome blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum
Home blood pressure measurement (HBPM) has the advantage of measuring blood pressure (BP) multiple times over a long period. HBPM effectively diagnoses stress-induced transient BP elevations (i.e., white coat ...
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Open AccessEffectiveness of antipsychotic drugs in schizophrenia: a 10-year retrospective study in a Korean tertiary hospital
Extensive research has been carried out on the comparative effectiveness of antipsychotic medications. Most studies, however, have been performed in Western countries. The purpose of this study was to compare ...
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Open AccessBlood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population-based cohort study
Little is known about age-specific target blood pressure (BP) in hypertensive patients with diabetes mellitus (DM). The aim of this study was to determine the BP level at the lowest cardiovascular risk of hype...
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Article
Open AccessLeft atrial longitudinal strain as a predictor of Cancer therapeutics-related cardiac dysfunction in patients with breast Cancer
We investigated the usefulness of the left atrial (LA) strain measurement on the prediction of upcoming cancer therapeutics-related cardiac dysfunction (CTRCD) after trastuzumab therapy in patients with breast...
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Open AccessComposite CDE: modeling composite relationships between common data elements for representing complex clinical data
Semantic interoperability is essential for improving data quality and sharing. The ISO/IEC 11179 Metadata Registry (MDR) standard has been highlighted as a solution for standardizing and registering clinical d...
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Application of deep learning to the diagnosis of cervical lymph node metastasis from thyroid cancer with CT
To develop a deep learning–based computer-aided diagnosis (CAD) system for use in the CT diagnosis of cervical lymph node metastasis (LNM) in patients with thyroid cancer.
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Open AccessClinical MetaData ontology: a simple classification scheme for data elements of clinical data based on semantics
The increasing use of common data elements (CDEs) in numerous research projects and clinical applications has made it imperative to create an effective classification scheme for the efficient management of the...
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Open Access2018 Korean Society of Hypertension guidelines for the management of hypertension: part I-epidemiology of hypertension
The Korean Society of Hypertension guideline defines hypertension as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, where the effectiveness of pharmacological treatment has been esta...
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Open Access2018 Korean society of hypertension guidelines for the management of hypertension: part III-hypertension in special situations
Treatment of hypertension improves cardiovascular, renal, and cerebrovascular outcomes. However, the benefit of treatment may be different according to the patients’ characteristics. Additionally, the target b...
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Article
Impacts of non-recovery of trastuzumab-induced cardiomyopathy on clinical outcomes in patients with breast cancer
The impacts of non-recovery of trastuzumab-induced left ventricular dysfunction (LVD) on clinical outcomes in breast cancer have been poorly studied. We investigated the predictors of LV-functional non-recover...
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Open Access2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension
The standardized techniques of blood pressure (BP) measurement in the clinic are emphasized and it is recommended to replace the mercury sphygmomanometer by a non-mercury sphygmomanometer. Out-of-office BP mea...
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Open AccessMolecular diagnosis of hereditary spherocytosis by multi-gene target sequencing in Korea: matching with osmotic fragility test and presence of spherocyte
Current diagnostic tests for hereditary spherocytosis (HS) focus on the detection of hemolysis or indirectly assessing defects of membrane protein, whereas direct methods to detect protein defects are complica...
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Article
Development of a Controlled Vocabulary-Based Adverse Drug Reaction Signal Dictionary for Multicenter Electronic Health Record-Based Pharmacovigilance
Integration of controlled vocabulary-based electronic health record (EHR) observational data is essential for real-time large-scale pharmacovigilance studies.
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Open AccessDevelo** a multi-center clinical data mart of ACEI and ARB for real-world evidence (RWE)
Randomized controlled trials can be expensive and time-consuming, leading to medical researchers utilizing real-world evidence (RWE) based on already-collected data. We aimed to conduct various RWE studies on ...
