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  1. No Access

    Article

    Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

    Caspase 8 is a cysteine protease regulated in both a death-receptor-dependent and -independent manner during apoptosis. Here, we report that the gene for caspase 8 is frequently inactivated in neuroblastoma, a...

    Tal Teitz, Tie Wei, Marcus B. Valentine, Elio F. Vanin, Jose Grenet… in Nature Medicine (2000)

  2. No Access

    Article

    Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma

    p58cdc2L1, a protein kinase implicated in apoptotic signaling, is one of eight separate kinases encoded by three tandemly duplicated and linked genes, which we have termed PITSLRE A, B and C. One allele of this c...

    Jill M. Lahti, Marcus Valentine, Jialing **ang, Bart Jones, Joseph Amann… in Nature Genetics (1994)