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Article
Open AccessDevelopment, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer
In cancer immunotherapy, the blockade of the interaction between programmed death-1 and its ligand (PD-1:PD-L1) has proven to be one of the most promising strategies. However, as mechanisms of resistance to PD...
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Article
The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement
A same-day PET imaging agent capable of measuring PD-L1 status in tumors is an important tool for optimizing PD-1 and PD-L1 treatments. Herein we describe the discovery and evaluation of a novel, fluorine-18 l...
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Chapter and Conference Paper
RoboCup@Home 2021 Domestic Standard Platform League Winner
Adoption of the World Robot Summit (WRS) rules and simulated environments for the RoboCup@Home Leagues in 2021 pose significant challenges for perception, manipulation and autonomy of the robot. Especially, th...
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Chapter and Conference Paper
STAR: Spatio-Temporal Prediction of Air Quality Using a Multimodal Approach
With the increase of global economic activities and high energy demand, many countries have raised concerns about air pollution. However, air quality prediction is a challenging issue due to the complex intera...
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Chapter and Conference Paper
Reliable Aggregation Method for Vector Regression Tasks in Crowdsourcing
Crowdsourcing platforms are widely used for collecting large amount of labeled data. Due to low-paid workers and inherent noise, the quality of acquired data could be easily degraded. To solve this, most prev...
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Article
Logistic regression model for sinkhole susceptibility due to damaged sewer pipes
The occurrence of anthropogenic sinkholes in urban areas can lead to severe socioeconomic losses. A damaged underground sewer pipe is regarded as one of the primary causes of such a phenomenon. This study adop...
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Article
Assessment of non-uniform deformation during consolidation with lateral drainage using Particle Image Velocimetry (PIV)
This paper experimentally investigates the lateral deformation characteristic of clay under consolidation with lateral drainage. A transparent consolidation test device was developed to obtain photo images of ...
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Article
Dynamic visualization of a joint-specific autoimmune response through positron emission tomography
In the K/BxN mouse model of rheumatoid arthritis, the transfer of autoantibodies specific for glucose-6-phosphate isomerase (GPI) into naïve mice rapidly induces joint-specific inflammation similar to that see...
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Chapter
Satisfiability-Based Functional Delay Fault Testing
Functional delay fault testing is concerned with propagating a transition from a primary input to a primary output of a combinational circuit. Since it does not consider individual paths in the circuit, it can...
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Article
Development of a simulation tool for the cornering performance analysis of 6WD/6WS vehicles
In this study, a simulation tool is developed to investigate non steady-state cornering performance of 6WD/6WS special-purpose vehicles. 6WD vehicles are believed to have good performance in off-the-road maneu...