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Article
Open AccessLong-term cardiovascular outcome in women with preeclampsia in Korea: a large population-based cohort study and meta-analysis
Recent studies reported the long-term cardiovascular risk of preeclampsia. However, only a few studies have investigated the association between preeclampsia and long-term cardiovascular disease in Asian popul...
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Open AccessAuthor Correction: Comprehensive characterization of maternal, fetal, and neonatal microbiomes supports prenatal colonization of the gastrointestinal tract
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Article
Open AccessManagement of the smaller twin with impending compromise in twin pregnancies complicated by selective fetal growth restriction: a questionnaire-based study of clinical practice patterns
In twin pregnancies complicated by selective fetal growth restriction (sFGR), if the smaller twin is in the state of impending intra-uterine death (IUD), immediate delivery will reduce the risk of IUD of the s...
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Article
Open AccessComprehensive characterization of maternal, fetal, and neonatal microbiomes supports prenatal colonization of the gastrointestinal tract
In this study, we aimed to comprehensively characterize the microbiomes of various samples from pregnant women and their neonates, and to explore the similarities and associations between mother-neonate pairs,...
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Article
Open AccessThe Skin Antiseptic agents at Vaginal dElivery (SAVE) trial: study protocol for a randomized controlled trial
Cleansing of the vulva and perineum is recommended during preparation for vaginal delivery, and special attention is paid to cleansing before episiotomy because episiotomy is known to increase the risk of peri...
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Article
Open AccessLong-term cardiovascular outcomes of gestational diabetes mellitus: a prospective UK Biobank study
Previous studies showed that gestational diabetes mellitus (GDM) can be a risk factor for subsequent atherosclerotic cardiovascular disease. However, there is a paucity of information regarding diverse cardiov...
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Article
Open AccessDevelopment of early prediction model for pregnancy-associated hypertension with graph-based semi-supervised learning
Clinical guidelines recommend several risk factors to identify women in early pregnancy at high risk of develo** pregnancy-associated hypertension. However, these variables result in low predictive accuracy....
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Open AccessPre-pregnancy blood pressure and pregnancy outcomes: a nationwide population-based study
Hypertension has been known to increase the risk of obstetric complications. Recently, the American College of Cardiology endorsed lower thresholds for hypertension as systolic blood pressure of 130-139 mmHg o...
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Article
Open AccessSimple and rapid detection of common fetal aneuploidies using peptide nucleic acid probe-based real-time polymerase chain reaction
To examine the detection performance of a peptide nucleic acid (PNA) probe-based real-time time polymerase chain reaction (PCR) assay to detect common aneuploidies. Using amniotic fluid samples, PNA probe base...
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Article
Open AccessMaternal dyslipidemia and altered cholesterol metabolism in early pregnancy as a risk factor for small for gestational age neonates
We evaluated the relationship between maternal cholesterol levels and its biologically active precursors and metabolites in the first trimester and subsequent risk for small-for-gestational-age birthweight (SG...
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Open AccessNovel method of real-time PCR-based screening for common fetal trisomies
The non-invasive prenatal test (NIPT) is based on next generation sequencing (NGS) and is used for screening for fetal trisomy. However, it is time-consuming and technically difficult. Recently, peptide nuclei...
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Article
Open AccessSelf-reported pain scores as a predictor of preterm birth in symptomatic twin pregnancy: a retrospective study
To evaluate the self-reported pain scores as a predictor of preterm birth (PTB) in symptomatic twin pregnancy and to develop a nomogram for the prediction model.
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Article
Open AccessAn evaluation of obstetric ultrasound education program in Nepal using the RE-AIM framework
Nepal has a high prevalence of congenital anomaly contributing to high infant mortality. Ultrasound, an important tool to detect congenital anomalies and manage maternity-related risk factors, is not properly ...
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Article
Open AccessMetabolomic biomarkers in midtrimester maternal plasma can accurately predict the development of preeclampsia
Early identification of patients at risk of develo** preeclampsia (PE) would allow providers to tailor their prenatal management and adopt preventive strategies, such as low-dose aspirin. Nevertheless, no mi...
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Open AccessMetabolic Biomarkers In Midtrimester Maternal Plasma Can Accurately Predict Adverse Pregnancy Outcome in Patients with SLE
Patients with systemic lupus erythematosus (SLE) are at increased risk for adverse pregnancy outcome (APO). Accurate prediction of APO is critical to identify, counsel, and manage these high-risk patients. We ...
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Open AccessEffects of antenatal corticosteroids in twin neonates with late preterm birth (ACTWIN [Antenatal Corticosteroids in TWIN late preterm neonates] trial): study protocol for a randomized controlled trial
Antenatal corticosteroids have been proven to prevent adverse outcomes including respiratory morbidities in preterm neonates before 34 weeks of gestation. Recently, it has been suggested that antenatal cortico...
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Article
Open AccessIncreased biosynthesis and accumulation of cholesterol in maternal plasma, but not amniotic fluid in pre-eclampsia
Preeclampsia is one of the most serious complications during pregnancy, defined as development of hypertension during late pregnancy affecting other organ systems (proteinuria, thrombocytopenia, renal insuffic...
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Article
Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus
Although there is substantial evidence that non-alcoholic fatty liver disease (NAFLD) is associated with impaired glucose homeostasis, the clinical significance of NAFLD in pregnant women has not been well det...
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Article
Open AccessSpontaneous corneal melting during pregnancy: a case report
Biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting.
