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  1. No Access

    Article

    Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population

    The human paraoxonase (PON) gene family includes three members: PON1, PON2, and PON3. PON, which prevents the oxidative modification of lipoproteins, has been implicated as a potential risk factor of the cereb...

    Hae Jeong Park, Su Kang Kim, Hyun-Kyung Park in Journal of Molecular Neuroscience (2015)

  2. No Access

    Article

    Protective Effect of Carbamazepine on Kainic Acid-induced Neuronal Cell Death Through Activation of Signal Transducer and Activator of Transcription-3

    Studies have shown that the protective effect of carbamazepine (CBZ) on seizure-induced neuronal injury. However, its precise mechanisms remain unknown. Here, to investigate the neuroprotective mechanism of CB...

    Hae Jeong Park, Su Kang Kim, Joo-Ho Chung in Journal of Molecular Neuroscience (2013)

  3. No Access

    Article

    Association of Toll-like Receptor 2 Polymorphisms with National Institute of Health Stroke Scale Scores of Ischemic Stroke Patients

    Toll-like receptor 2 (TLR2) has been shown to have an important role in the postischemic inflammatory response and to contribute to ischemic brain damage. In this study, we investigated whether coding region s...

    Hae Jeong Park, Su Kang Kim, Dong Hwan Yun in Journal of Molecular Neuroscience (2012)

  4. No Access

    Article

    Effect of Acupuncture on Hypothalamic–Pituitary–Adrenal System in Maternal Separation Rats

    The maternal separation (MS) animal model has been widely used to study early life stress and several psychiatric conditions such as depression and anxiety. In this study, we investigated the effect of acupunc...

    Hae Jeong Park, Hi Joon Park, Younbyoung Chae in Cellular and Molecular Neurobiology (2011)

  5. No Access

    Article

    Association of Polymorphism in the Promoter of the Melatonin Receptor 1A Gene with Schizophrenia and with Insomnia Symptoms in Schizophrenia Patients

    Schizophrenia patients commonly have sleep disturbances. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in the promoter region of the melatonin receptor genes (MTNR1A and MTNR1B)...

    Hae Jeong Park, ** Kyung Park, Su Kang Kim in Journal of Molecular Neuroscience (2011)

  6. Article

    Open Access

    Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population

    Arachidonic acid (AA), an essential polyunsaturated fatty acid, is one of the major components of neural membranes, which show an altered phospholipid composition in schizophrenia. Arachidonate 12-lipoxygenase (A...

    Tae Kim, Hak-Jae Kim, ** Kyung Park, Jong Woo Kim in Behavioral and Brain Functions (2010)

  7. Article

    Open Access

    No association between polymorphisms of WNT2and schizophrenia in a Korean population

    Wingless-type MMTV integration site family member 2 (WNT2) has a potentially important role in neuronal development; however, there has yet to be an investigation into the association between single nucleotide...

    Hak-Jae Kim, ** Kyung Park, Su Kang Kim, Sung Wook Kang in BMC Medical Genetics (2010)

  8. Article

    Open Access

    Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

    The occurrence of aberrant functional connectivity in the neuronal circuit is one of the integrative theories of the etiology of schizophrenia. Previous studies have reported that the protein and mRNA levels o...

    Hee Jae Lee, Ji Young Song, Jong Woo Kim, Sheng-Yu ** in Behavioral and Brain Functions (2005)

  9. Article

    Open Access

    Angiotensin converting enzyme gene polymorphism in Korean patients with primary knee osteoarthritis

    Angiotensin converting enzyme (ACE) plays an important role in the physiology of vasculature, blood pressure and inflammation. ACE gene, known to have insertion/deletion (I/D) polymorphism, has been widely inv...

    Seung-Jae Hong, Hyung-In Yang, Myung Chul Yoo in Experimental & Molecular Medicine (2003)

  10. Article

    Open Access

    Evaluation of a Apo-1/Fas promoter polymorphism in Korean stroke patients

    Apoptosis has been implicated in the pathogenesis of neurodegenerative diseases such as stroke and Alzheimer's disease. Apo-1/Fas gene is one of the mediators of apoptosis in stroke. MvaI polymorphism is the f...

    Jung-Chul Seo, Sang-Won Han, Chang-Sik Yin in Experimental & Molecular Medicine (2002)