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Article
Open AccessReporting quality of sham needles used as controls in acupuncture trials: a methodological evaluation
The description of controls is important in acupuncture clinical trials to interpret its effectiveness without fallacy. This paper aims to evaluate the reporting quality of acupuncture studies on the character...
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Open AccessEffect of acupuncture treatment in patients with mild to moderate atopic dermatitis: a randomized, participant- and assessor-blind sham-controlled trial
Atopic dermatitis (AD) is a chronic recurrent inflammatory skin disease that affects 1–3% of adults worldwide. Currently, it is not possible to completely cure AD; therefore, alternative treatments need to be ...
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Article
Open AccessOperant and classical learning principles underlying mind–body interaction in pain modulation: a pilot fMRI study
The operant conditioning has been less studied than the classical conditioning as a mechanism of placebo-like effect, and two distinct learning mechanisms have never been compared to each other in terms of the...
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Article
Open AccessEnhanced bodily states of fear facilitates bias perception of fearful faces
We investigated whether enhanced interoceptive bodily states of fear would facilitate recognition of the fearful faces. Participants performed an emotional judgment task after a bodily imagery task inside a fu...
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Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural network model
Comprehension of the medical diagnoses of doctors and treatment of diseases is important to understand the underlying principle in selecting appropriate acupoints. The pattern recognition process that pertains...
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Open AccessA retrospective cohort study on the outcomes of ischemic stroke patients with adjuvant Korean Medicine treatment
This study aims to examine the long-term effect of adjuvant treatment in Korean Medicine (KM) clinics in ischemic stroke patients, using a national sample cohort from the National Health Insurance Service in K...
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Article
Open AccessDoes different information disclosure on placebo control affect blinding and trial outcomes? A case study of participant information leaflets of randomized placebo-controlled trials of acupuncture
While full disclosure of information on placebo control in participant information leaflets (PILs) in a clinical trial is ethically required during informed consent, there have been concerning voices such comp...
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Open AccessWorld Congress Integrative Medicine & Health 2017: part two
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Acupuncture modulates brain neural activity in patients: a systematic review and meta-analysis
Using fMRI, the acupuncture studies related with modifying disease process in patients still stay in the beginning, whereas the physiological response to acupuncture has been published abundantly. In this stud...
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Open AccessWhat intrinsic factors influence responsiveness to acupuncture in pain?: a review of pre-clinical studies that used responder analysis
Not many studies have investigated individual sensitivity to acupuncture. To explore the intrinsic factors related to individual responses to acupuncture, we reviewed published pre-clinical studies using respo...
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Open AccessSpatiotemporal changes of optical signals in the somatosensory cortex of neuropathic rats after electroacupuncture stimulation
Peripheral nerve injury causes physiological changes in primary afferent neurons. Neuropathic pain associated with peripheral nerve injuries may reflect changes in the excitability of the nervous system, inclu...
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Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses
The protective and therapeutic mechanism of bee venom acupuncture (BVA) in neurodegenerative disorders is not clear. We investigated whether treatment with BVA (0.25 and 0.8 mg/kg) at the Zusanli (ST36) acupoi...
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Open AccessA new animal model of placebo analgesia: involvement of the dopaminergic system in reward learning
We suggest a new placebo analgesia animal model and investigated the role of the dopamine and opioid systems in placebo analgesia. Before and after the conditioning, we conducted a conditioned place preference...
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Open AccessCortical Activation Patterns of Bodily Attention triggered by Acupuncture Stimulation
We investigated commonalities and differences in brain responses to enhanced bodily attention around acupuncture points with and without stimulation. Fourteen participants received acupuncture needles at both ...
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Wound healing effect of acupuncture through activating angiogenesis in mice
In East Asian countries, acupuncture is used to treat wounds; however, the therapeutic mechanism is not well established. In this study, the effects of acupuncture on wound healing and the therapeutic mechanis...
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Neural substrates of acupuncture in the modulation of cravings induced by smoking-related visual cues: an FMRI study
Cue reactivity is a key factor in modulating motivational and goal-directed behaviors associated with compulsive drug intake and relapse. Smoking-associated cues produce smoking urges and cravings and are acco...
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Effect of Acupuncture on Hypothalamic–Pituitary–Adrenal System in Maternal Separation Rats
The maternal separation (MS) animal model has been widely used to study early life stress and several psychiatric conditions such as depression and anxiety. In this study, we investigated the effect of acupunc...
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The effect of electroaucpuncture for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced proteomic changes in the mouse striatum
Using a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Parkinson’s disease mouse model, we investigated protein expression changes associated with the action of electroacupuncture (EA) in the mouse striat...
