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Open AccessCorrection to: Editorial: Cancer metastasis through the lymphovascular system: molecular mechanisms of cancer metastasis
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Article
Open AccessEditorial: Cancer metastasis through the lymphovascular system: molecular mechanisms of cancer metastasis
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Article
Management of melanoma: can we use gene expression profiling to help guide treatment and surveillance?
Although the incidence of cutaneous melanoma (CM) has been increasing annually, the mortality rate has been decreasing, likely due to better prevention, earlier detection, improved surveillance, and the develo...
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Article
Open AccessIsolated hyperthermic perfusions for cutaneous melanoma in-transit metastasis of the limb and uveal melanoma metastasis to the liver
Patients with cutaneous melanoma can develop in-transit metastases (ITM), most often localized to limbs. For patients with uveal melanoma that develop metastatic disease, the overall majority develop isolated ...
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Article
Oncolytic intralesional therapy for metastatic melanoma
In-transit metastasis (ITM) develop in approximately 1 in 10 patients with melanoma and the disease course can vary widely. Surgical resection is the gold-standard treatment; however, ITM are often surgically ...
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Article
Dedication to late Dale Han, MD
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Article
Open AccessIntroduction: Novel Frontiers in Cancer Metastasis
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Open AccessEditorial: Novel Frontiers in Cancer Metastasis
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Open AccessFuture perspectives: Novel Frontiers in Cancer Metastasis
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In-transit metastatic cutaneous melanoma: current management and future directions
Management of in-transit melanoma encompasses a variety of possible treatment pathways and modalities. Depending on the location of disease, number of lesions, burden of disease and patient preference and char...
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Article
Sentinel lymph node biopsy in melanoma: beyond histologic factors
Sentinel lymph node (SLN) biopsy should be performed with the technical expertise required to correctly identify the sentinel node, in the context of understanding both the likelihood of positivity in a given ...
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Book
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Article
Perioperative Outcomes of Melanoma Patients Undergoing Surgery After Receiving Immunotherapy or Targeted Therapy
Traditional chemotherapy agents adversely affect wound healing and need to be held prior to or after surgery. Immune checkpoint inhibitors (ICIs) and targeted agents are now standard of care for the several tr...
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Chapter
Infusion Technique
Patients presenting with severe burden of disease with either in transit lesions or large, unresectable tumors, limited to a single limb, are generally not considered for surgical resection, as we aim to provi...
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Article
Robotic-Assisted Pelvic Lymphadenectomy for Metastatic Melanoma Results in Durable Oncologic Outcomes
Robotic pelvic lymphadenectomy (rPLND) has been demonstrated to be a safe and effective minimally invasive approach for patients with metastatic melanoma to the iliac nodes. However, the long-term oncologic be...
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Article
Behavior of Cutaneous Adnexal Malignancies: a Single Institution Experience
Cutaneous adnexal malignancies are biologically and pathologically diverse, and associated with a range of clinical outcomes. Given their rarity, the prognosis and optimal treatment of these neoplasms remains ...
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Chapter
Isolated Limb Perfusion and Infusion in the Management of In-Transit Melanoma of the Extremities: Modern Data Affecting Practice
Melanoma is an aggressive cutaneous malignancy that can recur in the form of in-transit lesions. In-transit disease can present challenges for both physician and patient, particularly when unresectable and bul...
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Chapter
Intralesional Therapies: Oncolytic Viral Therapies, Immunostimulants
In the last decade, there has been a dramatic change in the treatment landscape for cancer. With greater understanding in the mechanisms driving tumorigenesis, and the finding of cancer being closely linked wi...
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Reference Work Entry In depth
Isolated Limb Infusion for Melanoma
Isolated limb infusion (ILI) using melphalan and dactinomycin (actinomycin D) was developed as a simplified and minimally invasive alternative to the traditional, more invasive, and elaborative isolated limb p...
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Reference Work Entry In depth
Local and Recurrent Regional Metastases of Melanoma
Up to 10% of patients with cutaneous melanoma will develop recurrent locoregional disease. While surgical resection remains the mainstay of treatment for isolated recurrences, locoregional melanoma can often p...
