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  1. No Access

    Article

    Paternal Age is Negatively Associated with Religious Behavior in a Post-60s But Not a Pre-60s US Birth Cohort: Testing a Prediction from the Social Epistasis Amplification Model

    Participation in social behaviors that enhance group-level fitness may be influenced by mutations that affect patterns of social epistasis in human populations. Mutations that cause individuals to not particip...

    Michael A. Woodley of Menie, Satoshi Kanazawa… in Journal of Religion and Health (2020)

  2. Article

    Open Access

    Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice

    The schizophrenia-associated gene, BRD1, encodes an epigenetic regulator in which chromatin interactome is enriched with genes implicated in mental health. Alterations in histone modifications and epigenetic regu...

    Anto P. Rajkumar, Per Qvist, Julie G. Donskov, Ross Lazarus… in Translational Psychiatry (2020)

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    Article

    Genome-wide association study implicates CHRNA2 in cannabis use disorder

    Cannabis is the most frequently used illicit psychoactive substance worldwide; around one in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong genetic component, with twin herit...

    Ditte Demontis, Veera Manikandan Rajagopal, Thorgeir E. Thorgeirsson… in Nature Neuroscience (2019)

  4. No Access

    Article

    Identification of common genetic risk variants for autism spectrum disorder

    Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants contribute substantially to ASD susc...

    Jakob Grove, Stephan Ripke, Thomas D. Als, Manuel Mattheisen… in Nature Genetics (2019)

  5. No Access

    Article

    Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute substantially to ADHD suscept...

    Ditte Demontis, Raymond K. Walters, Joanna Martin, Manuel Mattheisen… in Nature Genetics (2019)

  6. Article

    Open Access

    Identification of the BRD1 interaction network and its impact on mental disorder risk

    The bromodomain containing 1 (BRD1) gene has been implicated with transcriptional regulation, brain development, and susceptibility to schizophrenia and bipolar disorder. To advance the understanding of BRD1 a...

    Tue Fryland, Jane H. Christensen, Jonatan Pallesen, Manuel Mattheisen… in Genome Medicine (2016)

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    Article

    Further immunohistochemical characterization of BRD1 a new susceptibility gene for schizophrenia and bipolar affective disorder

    We have recently shown that the gene BRD1 is associated with schizophrenia and bipolar affective disorder and that the BRD1 protein (BRD1) which is expressed in neurons may occur in a short and a long variant. Th...

    Carsten Reidies Bjarkam, Thomas J. Corydon… in Brain Structure and Function (2009)