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1128 INAPPROPRIATE ADH SYNDROME (IADH) AND PERSISTENT METABOLIC ACIDOSIS (PMA) IN NEONATAL PERIVENTRICULAR HEMORRHAGE (PVH)
PVH is the most common cause of death of LBW infants, accounting for 45% of deaths of infants < 1500 gm admitted to our ICU in 1976. To delineate the signs of PVH, we have analyzed the clinical findings of inf...
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138 PROSPECTIVE ANALYSIS OF PATENT DUCTUS ARTERIO-SUS (PDA) IN INBORN INFANTS < 1500 GM
Despite an increasing practice of ductal closure in the first 72h, neither the incidence of symptomatic PDA (sPDA) nor need for such aggressive therapy is clear. We have determined the incidence and onset of s...
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696 QUALITY OF PERINATAL THERAPEUTIC STUDIES
To assess studies which compare or recommend perinatal methods of treatment or management, all such studies (86) published in 1979 in J. Pediatrics, Pediatrics, Am. J. Ob.Gyn, and Ob.Gyn.were reviewed independ...
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Effect of Dietary Omega-3 Fatty Acids on Retinal Function of Very-Low-Birth-Weight Neonates
ABSTRACT: Retinal function was assessed by electroretinogram in 32 neonates randomly assigned to formulas of different ω-3 fatty acid content and in 10 infants fed human milk. All neonates had a birth weight o...
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OPTING-IN VS. OPTING-OUT: AN EXPLORATORY TRIAL OF TRADITIONAL AND MODIFIED INFORMED CONSENT FOR STUDIES WITH MINIMAL OR REDUCED RISK.• 236
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INACCURACY OF BALLARD SCORES IN ESTIMATING GESTATIONAL AGE (GA) OF 24-27 WEEKS INFANTS OF WOMEN WITH KNOWN MENSTRUAL HISTORY. † 1219
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Inter-center variation in concerns about ethical research design: Neonatal Network experience with Institutional Review Board (IRB) review.• 159
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CENTER DIFFERENCES IN SURVIVAL WITHOUT CHRONIC LUNG DISEASE (CLD) IN VERY-LOW-BIRTH-WEIGHT (VLBW) INFANTS ARE NOT EXPLAINED BY POPULATION DIFFERENCES, OR THE PRESENCE AND EARLY MANAGEMENT OF RESPIRATORY DISTRESS SYNDROME (RDS) • 1524
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Vitamin (Vit.) A Supplementation to Increase Survival without Chronic Lung Disease (CLD) in Extremely Low Birth Weight (ELBW) Infants: A 14-Center Randomized Trial • 1161
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Pattern of Improved Survival and Resource Utilization for Very Low Birth Weight (VLBW) Neonates (501-1500 gm) at Parkland Memorial Hospital Between 1977-1995 † 1275
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Does Seeking Informed Consent for Single or Multiple Studies Compromise Maternal Satisfaction? An Observational Study of Mothers of Very-Low-Birthweight Infants ♦ 166
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How Should Normal Values be Defined and Used for an Abnormal Population? Complexities Highlighted in a Multicenter Trial of Vitamin A Supplementation to Prevent Chronic Lung Disease (CLD) among Extremely Low Birth Weight(ELBW;≤1000 g) Infants 528
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Training Pediatric Residents in Evidence-Based Ethics: An Exploratory Clinical Trial ♦ 161
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Does Indomethacin Prophylaxis Benefit Extremely Low Birth Weight Infants? Results of a Placebo-Controlled Multicenter Trial
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The effects of aggressive vs. conservative phototherapy on the brainstem auditory evoked responses of extremely-low-birth-weight infants
This study was a two-center, stratified, parallel-group randomized trial comparing the effects of aggressive vs. conservative phototherapy on brainstem auditory evoked response (BAER) latencies in infants with...
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Cytokine profiles of preterm neonates with fungal and bacterial sepsis
Information on cytokine profiles in fungal sepsis (FS), an important cause of mortality in extremely low birthweight (ELBW) infants, is lacking. We hypothesized that cytokine profiles in the first 21 d of life...
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Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic–ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial
The effect of birth location on hypothermia-related outcomes has not been rigorously examined in the literature. In this study, we determined whether birth location had an impact on the benefits of whole-body ...
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Apolipoprotein E genotype and outcome in infants with hypoxic–ischemic encephalopathy
Adults with the apolipoprotein E (APOE) gene alleles e4 and e2 are at high risk of poor neurological outcome after brain injury. The e4 allele has been associated with cerebral palsy (CP), and the e2 allele ha...
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Open AccessComparative effectiveness of antihypertensive treatment for older children with primary hypertension: study protocol for a series of n-of-1 randomized trials
Children are increasingly being diagnosed with primary hypertension. The absence of comparative effectiveness research of antihypertensive medications in children has contributed to considerable differences in...
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Open AccessStop** guidelines for an effectiveness trial: what should the protocol specify?
Despite long-standing problems in decisions to stop clinical trials, stop** guidelines are often vague or unspecified in the trial protocol. Clear, well-conceived guidelines are especially important to assis...