-
Article
A Surgical Algorithm for the Management of Retrosternal Goiters
The heterogeneity of retrosternal goiter size, nearby anatomical structures, and evolving surgical techniques translates to difficulty in selecting the most appropriate surgical approach. Decades of experience...
-
Article
Self-perception of fatigue in individuals diagnosed with head and neck cancer
Head and neck cancer (HNCa) presents numerous challenges secondary to treatment. While there is substantial clinical awareness to the range of challenges demonstrated in this population, information on the imp...
-
Article
Variations of the thoracodorsal axis: application for scapular tip free flap harvesting
To illustrate variations of the vascular anatomy of the subscapular system highlighting practical implications on surgical access, patient positioning, and strategies to maximize the exposure of vascular pedicle.
-
Article
Open AccessBell’s palsy misdiagnosis: characteristics of occult tumors causing facial paralysis
The aim of this study was to report the incidence and clinical course of a series of patients who were misdiagnosed with Bell’s palsy and were eventually proven to have occult neoplasms.
-
Article
Open AccessSurgical margins of the oral cavity: is 5 mm really necessary?
Squamous cell carcinoma is the most common malignancy of the oral cavity. Primary treatment involves surgical resection of the tumour with a surrounding margin. Historically, the most commonly accepted margin ...
-
Article
Open AccessIntroduction and expression of PIK3CAE545K in a papillary thyroid cancer BRAFV600E cell line leads to a dedifferentiated aggressive phenotype
Anaplastic thyroid cancer (ATC) is a rare, aggressive form of undifferentiated thyroid cancer, which exhibits rapid progression and is almost universally fatal. At least a subset of ATC is thought to arise fro...
-
Article
Open AccessRapid standardized operating rooms (RAPSTOR) in thyroid and parathyroid surgery
To evaluate the impact of a high efficiency rapid standardized OR (RAPSTOR) for hemithyroid/parathyroid surgery using standardized equipment sets (SES) and consecutive case scheduling (CCS) on turnover times (...
-
Article
Resilience: an essential element in head and neck cancer survivorship and quality of life
Individuals with head and neck cancer (HNCa) face myriad biopsychosocial challenges. Even after treatment completion, these challenges may cause continued disablement and diminished quality of life (QoL). Resi...
-
Article
Open AccessModern treatment outcomes for early T-stage oropharyngeal cancer treated with intensity-modulated radiation therapy at a tertiary care institution
Transoral surgery (TOS), particularly transoral robotic surgery (TORS) has become the preferred modality in the United States for the treatment of early stage oropharyngeal cancer, largely due to assumptions o...
-
Article
Open AccessTAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma
Aberrant activation of the phosphatidylinositol 3-kinase (PI3K) pathway is common in many malignancies, including head and neck squamous cell carcinoma (HNSCC). Despite pre-clinical and clinical studies, outco...
-
Article
Open AccessRecommendations from the Canadian Association of Head and Neck Surgical Oncology for the Management of Head and Neck Cancers during the COVID-19 pandemic
The SARS-CoV-2 virus (COVID19) pandemic has placed extreme pressures on the Canadian Healthcare system. Many health care regions in Canada have cancelled or limited surgical and non-surgical interventions on p...
-
Article
Open AccessTreatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial
Patients with human papillomavirus-positive (HPV+) oropharyngeal squamous cell carcinoma (OPC) have substantially better treatment response and overall survival (OS) than patients with HPV-negative disease. Tr...
-
Article
Open AccessGenomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival
The genomic landscape of head and neck cancer has been reported through The Cancer Genome Atlas project. We attempt to determine if high-risk human papillomavirus (HPV) or frequently mutated genes are correlat...
-
Article
Novel minimally invasive transoral surgery bleeding model implemented in a nationwide otolaryngology emergencies bootcamp
Post-operative hemorrhage is the most concerning complication after minimally invasive transoral surgery, as can result in airway compromise. Simulation-based medical education provides trainees with structure...
-
Article
Open AccessUtility of clinical features with fine needle aspiration biopsy for diagnosis of Warthin tumor
Conservative management of Warthin tumor (WT) may be a viable alternative to surgery, but there are concerns of missed malignancies on fine needle aspiration biopsy (FNAB). The purpose of this study is to meas...
-
Chapter
Surgical Reconstruction for Cancer of the Oral Cavity
Surgical treatment for cancers of the head and neck in general, and for cancers of the oral cavity specifically, will often require that reconstruction is undertaken to improve functional and cosmetic outcomes...
-
Article
Open AccessFunctional outcomes in early (T1/T2) supraglottic cancer: a systematic review
Organ preserving surgery (OPS) and radiotherapy (RT) are both accepted treatment options for early stage supraglottic cancer (SGC). Radiation has supplanted surgery in most cases, because of the perception tha...
-
Article
Open AccessTreatment of early stage Supraglottic squamous cell carcinoma: meta-analysis comparing primary surgery versus primary radiotherapy
For early stage supraglottic squamous cell carcinoma (SCC), single modality treatment either in the form of primary organ preservation surgery alone or radiation alone is recommended. Thus, a definite treatmen...
-
Chapter
Customary International Law
Dans ce chapitre, nous étudions le débat sur la nature et les sources du Droit international coutumier. Le Droit international coutumier qui est le Droit qui lie les nations sans être exprimé dans des traités ...
-
Article
Open AccessSubtotal Parathyroidectomy and Relocation of the Parathyroid Remnant for Renal Hyperparathyroidism: modification of a traditional operation
We describe a modification of the conventional subtotal parathyroidectomy operation where the parathyroid gland(s) remnant is repositioned with intact vascular supply to a plane superficial to the infrahyoid s...
