6 Result(s)
within
John W Barnwell
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessThe first complete genome of the simian malaria parasite Plasmodium brasilianum
Naturally occurring human infections by zoonotic Plasmodium species have been documented for P. knowlesi, P. cynomolgi, P. simium, P. simiovale, P. inui, P. inui-like, P. coatneyi, and P. brasilianum. Accurate de...
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Article
Open AccessPlasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution
The genome sequences of the neglected human-infective malaria species Plasmodium malariae and P. ovale provide new insights into their biology that are pertinent to understanding their epidemiology and to the bro...
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Article
Open AccessEvaluation of the Illumigene Malaria LAMP: A Robust Molecular Diagnostic Tool for Malaria Parasites
Isothermal nucleic acid amplification assays such as the loop mediated isothermal amplification (LAMP), are well suited for field use as they do not require thermal cyclers to amplify the DNA. To further facil...
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Article
Open AccessMultiple genetic origins of histidine-rich protein 2 gene deletion in Plasmodium falciparum parasites from Peru
The majority of malaria rapid diagnostic tests (RDTs) detect Plasmodium falciparum histidine-rich protein 2 (PfHRP2), encoded by the pfhrp2 gene. Recently, P. falciparum isolates from Peru were found to lack pfhr...
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Article
Open AccessComparative genomics of the neglected human malaria parasite Plasmodium vivax
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the ∼515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical symptoms...
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Article
A new escape and evasion tactic
Mosquito-bornePlasmodium parasites that cause malaria have developed a variety of strategies to escape the defences put up by their hosts. A new one has been discovered in a Plasmodiumspecies that affects rodents...
