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Article
The role of focused ultrasound for pediatric brain tumors: current insights and future implications on treatment strategies
Focused ultrasound (FUS) is an innovative and emerging technology for the treatment of adult and pediatric brain tumors and illustrates the intersection of various specialized fields, including neurosurgery, n...
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Article
First-in-human sonodynamic therapy with ALA for pediatric diffuse intrinsic pontine glioma: a phase 1/2 study using low-intensity focused ultrasound
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Article
Prediction of shunt failure facilitated by rapid and accurate volumetric analysis: a single institution’s preliminary experience
Shunt malfunction is a common complication and often presents with hydrocephalus. While the diagnosis is often supported by radiographic studies, subtle changes in CSF volume may not be detectable on routine e...
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Article
Long-term outcomes of posterior fossa decompression for Chiari malformation type 1: which patients are most prone to failure?
The role of an osseous-only posterior fossa decompression (PFD) for Chiari malformation type 1 (CM1) remains controversial. We reviewed long-term outcomes for patients with CM1 undergoing a PFD to evaluate if the...
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Article
Long-term outcomes for children with an incidentally discovered Chiari malformation type 1: what is the clinical significance?
Chiari malformation type 1 (CM1) is an increasingly common incidental finding on magnetic resonance imaging (MRI). The proportion of children with an incidentally discovered CM1 who upon further evaluation req...
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Article
Cerebellar mutism syndrome: current approaches to minimize risk for CMS
Cerebellar mutism syndrome (CMS) is a serious source of morbidity following posterior fossa surgery in the pediatric population. However, methods for effectively decreasing its incidence and impact remain uncl...
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Reference Work Entry In depth
Ependymomas
Ependymomas are ependymal tumors of the brain and spinal cord of radial glial origin (Taylor et al. 2005). The medical community at large associates these lesions with posterior fossa tumors in children, but g...
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Living Reference Work Entry In depth
Ependymomas
Ependymomas are ependymal tumors of the brain and spinal cord of radial glial origin (Taylor et al. 2005). The medical community at large associates these lesions with posterior fossa tumors in children, but g...
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Article
Brainstem herniation into the internal acoustic canal secondary to hydrocephalus in context of spontaneous cerebrospinal fluid otorrhea: report of a novel entity
The authors report a case of a 5-year-old boy presenting with vision loss, right-sided hearing loss, and facial paralysis secondary to hydrocephalus causing brainstem herniation into the internal auditory cana...
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Article
Spatial heterogeneity in medulloblastoma
Michael Taylor, Marco Marra and colleagues analyze spatial tumor heterogeneity in 9 medulloblastomas, 16 high-grade gliomas and 10 renal cell carcinomas, using a combination of transcriptomic and genomic profi...
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Article
The gut or the brain?—gastrointestinal misdiagnoses of infantile brain tumors
Central nervous system tumors account for the largest number of cancer deaths in childhood. Brain tumors in infants less than 3 years of age are rare; symptoms and signs are often non-specific. Patent anterior...
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Article
Duplicated origin of a radiculomedullary artery supplying a perimedullary arteriovenous fistula: angiographic observation and developmental considerations
The angiographic observation of a radiculomedullary artery variation found in a patient with a spinal cord vascular malformation is presented. A posterior radiculomedullary artery arising from the left L2 inte...
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Chapter
Intramedullary Spinal Tumors in Children
Pediatric intramedullary spinal tumors (IMSTs) are generally uncommon, comprising 4–6% of all central nervous system (CNS) tumors and 35–40% of all intraspinal tumors in children [13, 21]. Of these, most are o...
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Article
Development of a Pediatric Neurocritical Care Service
To describe the development of a Pediatric Neurocritical Care (PNCCM) service; define the patient population that requires the service and describe important outcome parameters.