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  1. No Access

    Chapter

    Acute Hyperglycemia Does Not Affect Brain Swelling or Infarction Volume After Middle Cerebral Artery Occlusion in Rats

    Stroke disproportionally affects diabetic and hyperglycemic patients with increased incidence and is associated with higher morbidity and mortality due to brain swelling. In this study, the intraluminal suture...

    Devin W. McBride, Nathanael Matei, Justin R. Câmara… in Brain Edema XVI (2016)

  2. No Access

    Chapter

    Neurovascular Repair After Stroke

    Hemorrhagic strokes result from vessel rupture, increasing bleeding in the surrounding areas, and damaging adjacent tissues. The components of the blood and heme breakdown products induce toxicity, inflammatio...

    Sherrefa R. Burchell B.Sc.… in Non-Neuronal Mechanisms of Brain Damage an… (2016)

  3. No Access

    Chapter

    Statin-Induced T-Lymphocyte Modulation and Neuroprotection Following Experimental Subarachnoid Hemorrhage

    Introduction: Statins influence immune system activities through mechanisms independent of their lipid-lowering properties. T cells can be subdivided based on cytokine secretion patterns into two s...

    Robert E. Ayer M.D.… in Cerebral Vasospasm: Neurovascular Events A… (2013)

  4. No Access

    Chapter

    Magnesium in Subarachnoid Hemorrhage: From Bench to Bedside

    Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease responsible for 5 % of stroke cases and affects approximately 28,000 North Americans annually. Even though its incidence is dwarfed by other s...

    Jack Hou M.D., John H. Zhang M.D., Ph.D. in Magnesium in Human Health and Disease (2013)

  5. No Access

    Book

    Animal Models of Acute Neurological Injuries

    Jun Chen M.D., Zao C. Xu M.D., Ph.D.… in Springer Protocols Handbooks (2009)

  6. No Access

    Chapter and Conference Paper

    Multiple hyperbaric oxygenation (HBO) expands the therapeutic window in acute spinal cord injury in rats

    Hyperbaric oxygenation (HBO) therapy has been reported to improve neurological recovery following spinal cord injury (SCI). In the present study, we examined whether multiple HBO expands the therapeutic window...

    L. Huang, M. P. Mehta, J. H. Eichhorn, A. Nanda… in Brain Edema XII (2003)

  7. No Access

    Chapter and Conference Paper

    Apoptosis, blood-brain barrier, and subarachnoid hemorrhage

    This study was undertaken to investigate the role of apoptosis in the integrity of blood-brain barrier (BBB) in subarachnoid hemorrhage (SAH). BBB permeability changes were examined and found increased on day ...

    I. Gules, M. Satoh, A. Nanda, John H. Zhang M.D., Ph.D. in Brain Edema XII (2003)

  8. No Access

    Chapter and Conference Paper

    Heat shock proteins expression in brain stem after subarachnoid hemorrhage in rats

    The pathogenesis of brain damage after subarachnoid hemorrhage (SAH) especially at molecular or gene level remains unclear. We used complimentary deoxyribonucleic acid (cDNA) macroarray technique and compared ...

    M. Satoh, J. Tang, A. Nanda, John H. Zhang M.D., Ph.D. in Brain Edema XII (2003)

  9. No Access

    Chapter and Conference Paper

    Metabolic Alterations in Cerebrospinal Fluid from Double Hemorrhage Model of Dogs

    Even though cerebral vasospasm after subarachnoid hemorrhage (SAH) causes cerebral ischemia or infarction, the metabolic alterations in cerebrospinal fluids (CSF) after SAH have not been studied. This study wa...

    W. Yin, R. Tibbs, K. Aoki, A. Badr… in Intracranial Pressure and Brain Biochemica… (2002)

  10. No Access

    Chapter and Conference Paper

    Role of Tyrosine Kinase in Fibroblast Compaction and Cerebral Vasospasm

    Hemolysate, a proposed causative agent for cerebral vasospasm following subarachnoid hemorrhage, produces contraction of cerebral arteries by activation of tyrosine kinases. In addition, hemolysate accelerates...

    A. Patlolla, K. Ogihara, A. Zubkov, K. Aoki, A. D. Parent… in Brain Edema XI (2000)

  11. No Access

    Chapter and Conference Paper

    Oxyhemoglobin Produces Necrosis in Cultured Smooth Muscle Cells

    Object. Myonecrosis in the tunica media, which is defined morphologically, is one of the most striking alterations in the cerebral arterial wall following subarachnoid hemorrhage (SAH). In this s...

    K. Ogihara, A. Y. Zubkov, A. D. Parent, John H. Zhang M.D., Ph.D. in Brain Edema XI (2000)