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115 Result(s)
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Article
Open AccessElevated inflammatory biomarkers and poor outcomes in intracerebral hemorrhage
Accumulating evidence suggests that spontaneous intracerebral hemorrhage (ICH) is associated with a reactive neuroinflammatory response. However, it remains unclear if circulating inflammatory biomarkers are a...
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Article
Open AccessPredicting 10-year stroke mortality: development and validation of a nomogram
Predicting long-term stroke mortality is a clinically important and unmet need. We aimed to develop and internally validate a 10-year ischaemic stroke mortality prediction score. In this UK cohort study, 10,36...
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Open AccessPrevalence of orthostatic hypertension and its association with cerebrovascular diagnoses in patients with suspected TIA and minor stroke
We aimed to compare the rate of stroke, transient ischemic attack, and cerebrovascular disease diagnoses across groups of patients based on their orthostatic blood pressure response in a transients ischemic at...
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Open AccessPredictors of mortality and disability in stroke-associated pneumonia
Whilst stroke-associated pneumonia (SAP) is common and associated with poor outcomes, less is known about the determinants of these adverse clinical outcomes in SAP. To identify the factors that influence mort...
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Open AccessCan cardiovascular risk management be improved by shared care with general practice to prevent cognitive decline following stroke/TIA? A feasibility randomised controlled trial (SERVED memory)
Cognitive impairment and dementia following cerebrovascular disease are increasingly common in the UK. One potential strategy to prevent post-stroke cognitive decline is multimodal vascular risk factor managem...
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Open AccessSelf-Monitoring and Management of Blood Pressure in Patients with Stroke or TIA: An Economic Evaluation of TEST-BP, A Randomised Controlled Trial
Prevention of secondary stroke following initial ictus is an important focus of after-stroke care. Blood pressure (BP) is a key risk factor, so usual care following stroke or transient ischaemic attack include...
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Open AccessAssessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective observational study
There is a link between high on-treatment platelet reactivity (HPR) and adverse vascular events in stroke. This study aimed to compare multiple electrode platelet aggregometry (MEA), in healthy subjects and is...
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Open AccessEffectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review
Risks and prevalence of malnutrition and dehydration are high in older people but even higher in older people with dementia. In the EDWINA (Eating and Drinking Well IN dementiA) systematic review we aimed to a...
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Open AccessThe changes in clot microstructure in patients with ischaemic stroke and the effects of therapeutic intervention: a prospective observational study
Stroke is the second largest cause of death worldwide. Hypercoagulability is a key feature in ischaemic stroke due to the development of an abnormally dense clot structure but techniques assessing the mechanic...
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Article
Characteristics and determinants of survival in oldest old nursing home residents admitted to hospital with an acute illness compared to their younger counterparts
The clinical problems and needs of our oldest old (≥85 years) are often substantially different from those of younger patients, and are arguably different from younger elderly patients (age 65–84). With the in...
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Obituary: Dr. Michael Pugh Thomas (1932–2011)
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Erratum to: Incidence rates of exocrine and endocrine pancreatic cancers in the United States
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Article
Vital signs as determinants of immediate and longer term mortality outcome of patients admitted from Nursing Homes
Background and aims: Hospital admissions from Nursing Homes (NHs) are associated with high mortality. Identifying people with a poor prognosis admitted from NHs is essential to inform appropriate...
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Open AccessEvaluation of stroke services in Anglia stroke clinical network to examine the variation in acute services and stroke outcomes
Stroke is the third leading cause of death in developed countries and the leading cause of long-term disability worldwide. A series of national stroke audits in the UK highlighted the differences in stroke car...
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Obituary: Harvey F. Ludwig 1916–2010
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Incidence rates of exocrine and endocrine pancreatic cancers in the United States
Descriptive studies of pancreatic cancer incidence have been sparse particularly in terms of tumor histology and stage. The purpose of this study was to examine the incidence rate trends of exocrine and endocr...
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Open AccessControlling hypertension immediately post stroke: a cost utility analysis of a pilot randomised controlled trial
Elevated blood pressure (BP) levels are common following acute stroke. However, there is considerable uncertainty if and when antihypertensive therapy should be initiated.
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Article
Harvey F. Ludwig, Manual of environmental research for develo** countries
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Flooding and environmental challenges for Venice and its lagoon: State of knowledge, C. A. Fletcher and T. Spencer (eds.), 2005. Cambridge, Cambridge University Press, 691pp., ISBN 0-521-84046-5, £85, US$ 180 (hardback)
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Article
Infrastructure: A field guide to the industrial landscape, by Brian Hayes, 2005. New York, W. W. Norton & Co. Ltd., 536pp., ISBN 0-393-05997-9, £30, US$ 49.95 (hardback)