35 Result(s)
within
Jiyong **e
Biotechnology
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Article
Open AccessNanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppressi...
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Functionalized Green Carbon dots for Specific Detection of Copper in Human Serum Samples and Living Cells
Intracellular copper ion (Cu2+) is irreplaceable and essential in regulation of physiological and biological processes, while excessive copper from bioaccumulation may cause potential hazards to human health. Hen...
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Programmable A-to-Y base editing by fusing an adenine base editor with an N-methylpurine DNA glycosylase
Here we developed an adenine transversion base editor, AYBE, for A-to-C and A-to-T transversion editing in mammalian cells by fusing an adenine base editor (ABE) with hypoxanthine excision protein N-methylpuri...
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Open Accessαvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma
Melanoma is the most malignant skin tumor and is difficult to cure with the alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study showed that triptolide (TP) exhibited powerful...
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Article
Cryopreservation Engineering Strategies for Mass Production of Adipose-Derived Stem Cells
Cryopreservation is required for the manufacturing and large-scale production of adipose-derived stem cell (ADSC)-mediated therapeutics. For both autologous ADSC products for patient-specific therapeutics and ...
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A Brief Overview of Recent Engineering Approaches for Intervertebral Disc Regeneration Using Adipose Derived Mesenchymal Stem Cell Administration
Intervertebral disc (IVD) degeneration and subsequent low back pain (LBP) are major orthopedic diseases worldwide. IVD herniation could be caused by an accidental trauma or posture imbalance. When the symptoms...
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Improved Simultaneous Decolorization and Power Generation in a Microbial Fuel Cell with the Sponge Anode Modified by Polyaniline and Chitosan
In recent years, microbial fuel cell (MFC) has been regarded as a promising technology for dye wastewater treatment. Compared with traditional anaerobic reactors, MFC has better decolorization effect while pro...
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Antioxidant, antidiabetic and identification of phenolic constituents from Potentilla discolor Bge.
The objective of this study was to investigate the antioxidant and enzyme inhibitory activity, and characterize the bioactive constituents of the phenolic extract of Potentilla discolor Bge. Dry material of Poten...
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Quantitative risk assessment of an amine-based CO2 capture process
This study presents a risk assessment study on an amine-based CO2 capture process. Based on the critical risks identified by a hazard and operability study (HAZOP) conducted in our previous work, we performed det...
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Construction of an infectious bronchitis virus vaccine strain carrying chimeric S1 gene of a virulent isolate and its pathogenicity analysis
Infectious bronchitis virus (IBV) is a member of genus gamma-coronavirus in the family Coronaviridae, causing serious economic losses to the poultry industry. Reverse genetics is a common technique to study the b...
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Transcriptomic analysis of resistant and susceptible cabbage lines reveals differential expressions and candidate genes involved in cabbage early responses to black rot
Cabbage (Brassica oleracea var. capitata) is one of the most important cruciferous leafy vegetable crops and is widely cultivated all over the world. Its yield and quality are often affected by diseases such as c...
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Improved Postharvest Quality of Cold Stored Blueberry by Edible Coating Based on Composite Gum Arabic/Roselle Extract
The present work aimed at evaluating the efficacy of gum Arabic–based edible coating enriched with red and white roselle extracts, on the postharvest quality of blueberry fruits during storage at 4 ± 0.5 °C. P...
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Open AccessA novel macrophage-mediated biomimetic delivery system with NIR-triggered release for prostate cancer therapy
Macrophages with tumor-tropic migratory properties can serve as a cellular carrier to enhance the efficacy of anti neoplastic agents. However, limited drug loading (DL) and insufficient drug release at the tum...
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Review of MXenes as new nanomaterials for energy storage/delivery and selected environmental applications
Energy and environmental issues presently attract a great deal of scientific attention. Recently, two-dimensional MXenes and MXene-based nanomaterials have attracted increasing interest because of their unique...
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Open AccessComprehensive evaluation of fuel properties and complex regulation of intracellular transporters for high oil production in develo** seeds of Prunus sibirica for woody biodiesel
Based on our previous studies of 17 Prunus sibirica germplasms, one plus tree with high quality and quantity of seed oils has emerged as novel potential source of biodiesel. To better develop P. sibirica seed oil...
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Open AccessLipid nanoparticles loading triptolide for transdermal delivery: mechanisms of penetration enhancement and transport properties
In recent years, nanoparticles (NPs) including nanostructured lipid carries (NLC) and solid lipid nanoparticles (SLN) captured an increasing amount of attention in the field of transdermal drug delivery system...
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Monoclonal antibody against the universal M2 epitope of influenza A virus
M2 protein, a highly conserved protein of influenza A virus (IAV), plays an important role in virus particle uncoating, assembly, and budding. In the present study, eight monoclonal antibodies (mAbs) against t...
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Techno-economic evaluation of gas separation processes for long-term operation of CO2 injected enhanced coalbed methane (ECBM)
Energy source diversification through development of coalbed methane (CBM) resources is one of the key strategies to make a country less dependent on simple energy resources (e.g., crude oil, natural gas, nucl...
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Open AccessDevelopment of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics
This work aimed to provide useful information on the use of nanoemulsions for the percutaneous administration of triptolide. Lipid nanosystems have great potential for transdermal drug delivery. Nanoemulsions ...
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Analysis of a major rice blast resistance gene in the rice restorer line Hanghui 1179
Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is one of the most devastating diseases of rice (Oryza sativa) worldwide. Identification and utilization of resistance genes in rice breeding is consi...
