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Article
Open AccessActivation of TCA cycle restrains virus-metabolic hijacking and viral replication in mouse hepatitis virus-infected cells
One of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused coronavirus disease 2019 (COVID-19) pandemic and threatened worldwide. However, therapy for COVID-19 has rarely been...
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Article
Open AccessHeat shock protein 70 could enhance porcine epidemic diarrhoea virus replication by interacting with membrane proteins
In this study, we investigated the role of heat shock protein 70 (HSP70) in porcine epidemic diarrhoea virus (PEDV) replication. We found that PEDV infection induced strong HSP70 overexpression in the very ear...
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Article
Open AccessRelevance of mortalin to cancer cell stemness and cancer therapy
Mortalin/mtHsp70 is a member of Hsp70 family of proteins. Enriched in a large variety of cancers, it has been shown to contribute to the process of carcinogenesis by multiple ways including inactivation of tum...
