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Article
Urate-lowering agents do not have clinically relevant negative effects on sperm quality and reproductive hormones in men with gout: a prospective open-label cohort study
The objective of this study was to analyze and compare the effects of different urate-lowering agents on testicular functions in men with gout in a clinical setting.
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Multiplexed in situ RNA imaging by combFISH
Multiplexed in situ RNA imaging offers new opportunities for gene expression profiling by providing high-throughput spatial information. In this work, we present a cyclic combinatorial fluorescent in situ hybridi...
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A marigold corolla detection model based on the improved YOLOv7 lightweight
Marigold, as an important traditional Chinese medicinal plant renowned for its therapeutic attributes in heat dissipation, detoxification, liver protection, facial enhancement, and promotion of eye health, has...
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Effect of minor Sb addition on microstructure, interfacial behavior, and mechanical properties of Sn–15Bi solder joints
This paper focuses on the effect of adding minor Sb with different content (1–3 wt.%) into Sn–15Bi solder to improve the microstructure, mechanical properties, and interfacial behavior of solder joints. The in...
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Open AccessAssociation between metabolic score of visceral fat and carotid atherosclerosis in Chinese health screening population: a cross-sectional study
The metabolic score for visceral fat (METS-VF) quantifies the cumulative burden of visceral and intra-abdominal adipose tissues. However, the relationship between the METS-VF and carotid atherosclerosis (CAS) ...
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Open AccessSequence-specific dynamic DNA bending explains mitochondrial TFAM’s dual role in DNA packaging and transcription initiation
Mitochondrial transcription factor A (TFAM) employs DNA bending to package mitochondrial DNA (mtDNA) into nucleoids and recruit mitochondrial RNA polymerase (POLRMT) at specific promoter sites, light strand pr...
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Open AccessPatients with ASPSCR1-TFE3 fusion achieve better response to ICI based combination therapy among TFE3-rearranged renal cell carcinoma
TFE3-rearranged renal cell carcinoma (TFE3-rRCC) is a rare but highly heterogeneous renal cell carcinoma (RCC) entity, of which the clinical treatment landscape is largely undefined. This study aims to evaluate a...
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Open AccessConstructing and implementing a performance evaluation indicator set for artificial intelligence decision support systems in pediatric outpatient clinics: an observational study
Artificial intelligence (AI) decision support systems in pediatric healthcare have a complex application background. As an AI decision support system (AI-DSS) can be costly, once applied, it is crucial to focu...
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Open AccessEffects of different types of exercise intensity on improving health-related physical fitness in children and adolescents: a systematic review
A substantial body of empirical evidence reveals that physical activity is associated with a wide range of positive physical and mental health outcomes. However, an absence of comprehensive syntheses is observ...
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Open AccessPolymer Fiber Rigid Network with High Glass Transition Temperature Reinforces Stability of Organic Photovoltaics
A unique approach is proposed: constructing a polymer fiber rigid network with high glass transition temperature.
Frozen bul...
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Open AccessQualitative and quantitative assessment of non-clear cell renal cell carcinoma using contrast-enhanced ultrasound
Non-clear cell renal cell carcinoma (nccRCC) represents a rare form of renal cell carcinoma (RCC) in the clinic. It is now understood that contrast-enhanced ultrasound (CEUS) exhibits diverse manifestations an...
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Atmosphere-dependent combustion of Ganoderma lucidum biomass toward its enhanced transformability into green energy
Globally, the circular efficiency of biomass resources has become a priority due to the depletion and negative environmental impacts of fossil fuels. This study aimed to quantify the atmosphere-dependent combu...
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Research on the effect of recombustion treatment on the performance of straw biomass fly ash
The use of biomass fly ash (BFA) as a substitute for cementitious materials is an effective way of recycling waste products. However, the presence of unburned particles in biomass fly ash limits its utilizatio...
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Celastrol Regulates the Hsp90-NLRP3 Interaction to Alleviate Rheumatoid Arthritis
Previous studies have verified that celastrol (Cel) protects against rheumatoid arthritis (RA) by inhibiting the NLRP3 inflammasome signaling pathway, but the molecular mechanism by which Cel regulates NLRP3 h...
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A discontinuous Galerkin method for Maxwell’s transmission eigenvalue problem
We propose an interior penalty discontinuous Galerkin (IPDG) method for the Maxwell’s transmission eigenvalue problem. First we reformulate the problem as a parameterized eigenvalue problem and define the fixe...
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Open AccessEctopic adrenocortical adenoma characterized by hypogonadism: a case report and review of the literature
Currently, there is a scarcity of cases and diagnostic data regarding ectopic adrenocortical adenomas, particularly in relation to their impact on gonadal function and localization diagnostic techniques. We re...
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Open AccessCo-evolution of vaginal microbiome and cervical cancer
Exploration of adaptive evolutionary changes at the genetic level in vaginal microbial communities during different stages of cervical cancer remains limited. This study aimed to elucidate the mutational profi...
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Microwave-accelerated direct regeneration of LiCoO2 cathodes for Li-ion batteries
Recycling spent lithium-ion batteries is integral to today’s low-carbon environmental protection efforts. The concept of direct regeneration, acknowledged for its environmental sustainability, economic viabili...
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Open AccessComprehensive characterization of B7 family members in breast cancer: B7-H5 switch reverses breast cancer from “immuno-cold” into “immuno-hot” status
The members of the classic B7 family regulate the immune microenvironment of several malignant tumors. However, the potential relationship between the B7 family and the breast cancer (BrCa) tumor immune microe...
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Distinguishing high-metastasis-potential circulating tumor cells through fluidic shear stress in a bloodstream-like microfluidic circulatory system
Circulating tumor cells (CTCs) play a critical role as initiators in tumor metastasis, which unlocks an irreversible process of cancer progression. Regarding the fluid environment of intravascular CTCs, a comp...
