164 Result(s)

Article

Constructing and implementing a performance evaluation indicator set for artificial intelligence decision support systems in pediatric outpatient clinics: an observational study

Artificial intelligence (AI) decision support systems in pediatric healthcare have a complex application background. As an AI decision support system (AI-DSS) can be costly, once applied, it is crucial to focu...

Yingwen Wang, Weijia Fu, Yuejie Zhang, Daoyang Wang, Ying Gu… in Scientific Reports (2024)

Article

Isotemporal substitution of accelerometer-derived sedentary behavior and physical activity on physical fitness in young children

This study investigates the effects of different types of physical activity (PA) on the physical fitness (PF) of young children in Japan, with a particular focus on how substituting sedentary behavior (SB) wit...

Ying Gu, Junghoon Kim, Jiameng Ma, Hongzhi Guo, Hiroko Sano… in Scientific Reports (2024)

Article

Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains

The vaccine elicitation of HIV tier-2-neutralization antibodies has been a challenge. Here, we report the isolation and characterization of a CD4-binding site (CD4bs) specific monoclonal antibody, HmAb64, from...

Shixia Wang, Kun-Wei Chan, Danlan Wei, **uwen Ma, Shuying Liu… in Nature Communications (2024)

Article

Effects of electronic screen exposure time on hypertensive disorders in pregnancy: a retrospective cohort study

We previously conducted a case-control study and found that exposure to electronic screen before nocturnal sleep was associated with hypertensive disorders in pregnancy (HDP). Hence, we carried out this cohort...

Shaidi Tang, Yun Liu, Ying Gu, Qianqian Yang, Qian Wang in BMC Public Health (2024)

Article

Social drug dealing: how peer-to-peer fintech platforms have transformed illicit drug markets

Digital platforms have revolutionized the way illegal drug trafficking is taking place. Modern drug dealers use social network platforms, such as Instagram and TikTok, as direct-to-consumer marketing tools. Bu...

Jörn Boehnke, Pantelis Loupos, Ying Gu in Annals of Operations Research (2024)

Article

Correction to: Simultaneous and rapid detection of polychlorinated phenols in water samples by surface‑enhanced Raman spectroscopy combined with principal component analysis

Kun Ge, Yonghui Li, Qiyue Wu, Ying Gu in Analytical and Bioanalytical Chemistry (2024)

Article

Deviations in continuously monitored electrodermal activity before severe clinical complications: a clinical prospective observational explorative cohort study

Monitoring of high-risk patients in hospital wards is crucial in identifying and preventing clinical deterioration. Sympathetic nervous system activity measured continuously and non-invasively by Electrodermal...

Andreas Ohrt Johansen, Jesper Mølgaard… in Journal of Clinical Monitoring and Computi… (2023)

Article

Identification of a novel NPM1 mutation in acute myeloid leukemia

Nucleophosmin (NPM1) is a widely expressed nucleocytoplasmic shuttling protein with prominent nucleolar localization. It is estimated that 25–35% of adult patients with acute myeloid leukemia (AML) carry NPM1 mut...

Yiyi Yao, **angjie Lin, Chen Wang, Ying Gu, Jie **… in Experimental Hematology & Oncology (2023)

Article

A novel modified-curcumin 2.24 resolves inflammation by promoting M2 macrophage polarization

To assess resolving-like activity by a novel chemically-modified curcumin (CMC2.24) in a “two-hit” model of diabetes-associated periodontitis. Macrophages from rats were cultured in the presence/absence of eit...

Jie Deng, Lorne M. Golub, Hsi-Ming Lee, Heta-Dinesh Bhatt… in Scientific Reports (2023)

Article

A scATAC-seq atlas of chromatin accessibility in axolotl brain regions

Axolotl (Ambystoma mexicanum) is an excellent model for investigating regeneration, the interaction between regenerative and developmental processes, comparative genomics, and evolution. The brain, which serves a...

Weimin Feng, Shuai Liu, Qiuting Deng, Sulei Fu, Yunzhi Yang, ** Dai… in Scientific Data (2023)

Article

Peroxisomal compartmentalization of amino acid biosynthesis reactions imposes an upper limit on compartment size

Cellular metabolism relies on just a few redox cofactors. Selective compartmentalization may prevent competition between metabolic reactions requiring the same cofactor. Is such compartmentalization necessary ...

Ying Gu, Sara Alam, Snezhana Oliferenko in Nature Communications (2023)

Article

Preventing Post-Traumatic Stress Disorder (PTSD) in rats with pulsed 810 nm laser transcranial phototherapy

Post-traumatic stress disorder (PTSD) is a debilitating condition that occurs following exposure to traumatic events. Current treatments, such as psychological debriefing and pharmacotherapy, often have limite...

Hongyou Zhao, Yi Li, Ting Luo, Wenxin Chou, Tianzhen Sun… in Translational Psychiatry (2023)

Article

Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

Glioblastoma (GBM) is the most frequent malignant brain tumor, the relapse of which is unavoidable following standard treatment. However, the effective treatment for recurrent GBM is lacking, necessitating the...

**n Wang, Qian Sun, Weiwen Wang, Baohui Liu… in Acta Neuropathologica Communications (2023)