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Article
Open AccessClinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review
The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pat...
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Article
Carbon, nitrogen, and phosphorus metabolic relationships and reaction mechanisms in SBBR processes in the plateau habitat
In this study, two laboratory-scale SBBR reactors were established in a plateau habitat. Using high flux sequencing, the SBBR process was compared by natural sediment and autotrophic sludge to characterize the...
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Article
Open AccessTranslation and validation of the Chinese ABCD risk questionnaire to evaluate adults’ awareness and knowledge of the risks of cardiovascular diseases
Assessment of health beliefs and risk perception is a critical means to prevent coronary heart disease, but there are few such studies on assessment in the Chinese population. Given the demonstrated value and ...
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Article
Open AccessPFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation
Cancer cells adopt metabolic reprogramming to promote cell survival under metabolic stress. A key regulator of cell metabolism is AMP-activated protein kinase (AMPK) which promotes catabolism while suppresses ...
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Article
Open AccessBroadband bifunctional Luneburg–Fisheye lens based on anisotropic metasurface
Luneburg lenses and Maxwell fisheye lenses possess distinct properties of focusing, well beyond conventional lenses made of uniform materials. In this paper, a planar broadband bifunctional Luneburg-fisheye le...
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Chapter and Conference Paper
Design and Implementation of Key Extension and Interface Module Based on Quantum Circuit
Encryption technology that based on quantum circuit is an important technology in the field of information security and the encryption system designed by this technology can improve the encryption effect, and ...
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Article
A New Flavone from Flos Sophorae Immaturus Through Microbial Transformation by Nigrospora sphaerica ZMT05
A new flavone derivative, 3′-(γ,γ-dimethylallyloxy)-5,7-dihydroxy-4′-methoxyflavone (1), was isolated from Flos Sophorae Immaturus through microbial transformation by the fungus Nigrospora sphaerica ZMT05. Its st...
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Article
Joint model-based clustering of nonlinear longitudinal trajectories and associated time-to-event data analysis, linked by latent class membership: with application to AIDS clinical studies
Longitudinal and time-to-event data are often observed together. Finite mixture models are currently used to analyze nonlinear heterogeneous longitudinal data, which, by releasing the homogeneity restriction o...
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Article
Adsorptive removal of organics from aqueous phase by acid-activated coal fly ash: preparation, adsorption, and Fenton regenerative valorization of “spent” adsorbent
Raw coal fly ash was activated to an adsorbent by sulfuric acid impregnation. The activation condition, the adsorption capacity, and the regenerative valorization of the adsorbent were studied. The results sho...
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Article
Open AccessTime-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats
Lipopolysaccharide (LPS) can lead to uncontrollable cytokine production and eventually cause fatal sepsis syndrome. Individual toxicity difference of LPS has been widely reported. In our study we observed that...
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Article
Perspectives on Animal Models Utilized for the Research and Development of Regenerative Therapies for Articular Cartilage
Animal models are integral and indispensable for biomedical research and regenerative medicine studies, as these provide invaluable information for systemically evaluating the potential risks and efficacy of n...
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Article
A novel liquid chromatography tandem mass spectrometry method for simultaneous determination of branched-chain amino acids and branched-chain α-keto acids in human plasma
Branched-chain amino acids (BCAAs) and branched-chain α-keto acids (BCKAs) play significant biological roles as they are involved in protein and neurotransmitter synthesis as well as energy metabolism pathways...
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Article
Distractor removal amplifies spatial frequency-specific crossover of the attentional bias: a psychophysical and Monte Carlo simulation study
Rarely noticed in daily life, attention may prefer the left side of space. Such attentional biases offer key insights into functions of spatial attention and visual awareness because they complement pathologic...
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Article
Do head-on-trunk signals modulate disengagement of spatial attention?
Body schema is indispensable for sensorimotor control and learning, but whether it is associated with cognitive functions, such as allocation of spatial attention, remains unclear. Observations in patients wi...
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Article
Two-sided Empirical Bayes test for the exponential family with contaminated data
In this study, the two-sided Empirical Bayes test (EBT) rules for the parameter of continuous one-parameter exponential family with contaminated data (errors in variables) are constructed by a deconvolution ke...
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Chapter and Conference Paper
Influence of the Bar Shape on the Welding Quality of Friction Hydro Pillar Processing
Traditional underwater arc welding methods, for example, TIG and MIG, are generally expensive and complex to implement under water. Besides, the welding quality decreases significantly with the increase of dep...
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Chapter and Conference Paper
Study on Sub-sea Pipelines Hyperbaric Welding Repair under High Air Pressures
Most Chinese sub-sea pipelines are buried in Bohai Sea less than 60m water depth, where air diving are widely used For the application of offshore pipelines repair, the hyperbaric TIG welding process under hig...