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Article
Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling
Pancreatic cancer has been a serious disease worldwide for its high mortality. Cucurbitacin E is a member of triterpenoid family isolated from plants showing antiproliferative activity on various cancer cells....
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Article
Traumatic Brain Injury Induces an Up-Regulation of Hs1-Associated Protein X-1 (Hax-1) in Rat Brain Cortex
HS1-associated protein X-1 (Hax-1) is an intracellular protein with anti-apoptotic properties that, in addition to suppressing cell death by inhibiting the activation of initiator caspase-9 and death caspase-3...
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Article
Upregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injury
p21-activated Kinase 6 (PAK6) is a serine/threonine kinase belonging to the p21-activated kinase (PAK) family. PAK kinases are well-known regulators of a wide variety of cellular functions, including regulatio...
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Article
Hydrogen peroxide detection using a polypyrrole/Prussian blue nanowire modified electrode
A hydrogen peroxide sensor based on a polypyrrole (PPy)/Prussian blue (PB) modified electrode was developed. PPy nanowires were prepared by one step template-free electrochemical polymerization on a gold elect...
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Article
Research of the relationship between radiotherapy and microRNAs
MicroRNAs (miRNAs) are endogenous short non-coding RNAs, and play a pivotal role in regulating a variety of cellular processes, including proliferation and apoptosis, both of which are cellular responses to ra...
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Article
Induction of epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma after radiotherapy
Epithelial-mesenchymal transition (EMT) is a critical early event for the invasion and metastasis of many carcinomas. In the present study, we examined EMT markers in the residual cancer cells of hepatocellula...
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Article
DNA repair genes BRCA1 and DNA-PKcs have great potential in radiation therapy
Radiotherapy is a part of the front-line treatment regime for many cancers. The mechanisms of radiation-induced effects in cancers mainly involves double-strand breaks (DBS) which plays very important role in ...
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Chapter and Conference Paper
A Sequential Multi-Signature Scheme Based on ElGamal Meteorological File
In this paper, a sequential multi-signature scheme based on ElGamal algorithm was presented, which allows multiple signers to sign the same message. This scheme used zero-knowledge proof during the part of key...
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Article
Temporal-Spatial Expressions of Spy1 in Rat Sciatic Nerve After Crush
As a novel cell cycle protein, Spy1 enhances cell proliferation, promotes the G1/S transition as well as inhibits apoptosis in response to UV irradiation. Spy1 levels are tightly regulated during mammary devel...
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Article
Changes in the BAG1 Expression of Schwann Cells After Sciatic Nerve Crush
Bcl-2-associated athanogene-1 (BAG1), a co-chaperone for Hsp70/Hsc70, is a multifunctional protein, which has been shown to suppress apoptosis and enhance neuronal differentiation. However, the expression and ...
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Article
Transcription Initiation Factor IIB Involves in Schwann Cell Differentiation after Rat Sciatic Nerve Crush
Transcription Initiation Factor IIB (TFIIB), as a general transcription factor, plays an essential role in preinitiation complex assembly and transcription initiation by recruiting RNA polymerase II to the pro...
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Article
Spatiotemporal Expression of SKIP After Rat Sciatic Nerve Crush
Ski-interacting protein (SKIP) is a highly conserved protein from yeast to Human. As an essential spliceosomal component and transcriptional co-regulator it plays an important role in preinitiation, splicing a...
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Article
Open AccessThe characteristics and expression profiles of the mitochondrial genome for the Mediterranean species of the Bemisia tabacicomplex
The whiteflies under the name Bemisia tabaci (Gennadius) (Aleyrodidae: Hemiptera) are species complex of at least 31 cryptic species some of which are globally invasive agricultural pests. Previously, the mitocho...
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Article
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
The 70-kDa heat-shock protein 70 (Hsp70) molecular chaperones have a nucleotide binding domain and a substrate binding domain that become allosterically coupled when Hsp70s bind ATP. The crystal structure of t...
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Article
Cytokine-induced killer cell combination with TACE in the treatment of hepatocellular cancers: a meta-analysis
The aim of the study was to evaluate the efficacy and safety of cytokine-induced killer (CIK) cell combined with transcatheter arterial chemoembolization (TACE) therapy in the treatment of hepatocellular carci...
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Article
Open AccessRoles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells
Mouse embryonic stem (ES) cell cultures exhibit heterogeneity and recently are discovered to sporadically enter the 2-cell (2C)-embryo state, critical for ES potency. Zscan4 could mark the sporadic 2C-state of ES...
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Article
Role of pH in structural changes for Pin1 protein: an insight from molecular dynamics study
Pin1 protein is closely associated with the pathogenesis of cancers and Alzheimer’s disease (AD). Previously, we have shown the acid-induced denaturation of Pin1 was determined by means of fluorescence emissio...
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Article
Chemical modification with functionalized ionic liquids: a novel method to improve the enzymatic properties of Candida rugosa lipase
Chemical modification of lysine residues in Candida rugosa lipase (CRL) was carried out using five different functional ionic liquids, and about 15.4–25.0 % of the primary amino groups of lysine were modified. En...
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Article
Open AccessSynthesis of multi-shelled ZnO hollow microspheres and their improved photocatalytic activity
Herein, we report an effective, facile, and low-cost route for preparing ZnO hollow microspheres with a controlled number of shells composed of small ZnO nanoparticles. The formation mechanism of multiple-shel...
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Article
Open AccessDevelo** conversed microsatellite markers and their implications in evolutionary analysis of the Bemisia tabaci complex
The study of population genetics among the Bemisia tabaci complex is limited due to the lack of conserved molecular markers. In this study, 358, 433 and 322 new polynucleotide microsatellites are separately ident...
