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Article
The chromosomal characteristics of spontaneous abortion and its potential associated copy number variants and genes
This study aimed to investigate the correlation between chromosomal abnormalities in spontaneous abortion with clinical features and seek copy number variations (CNVs) and genes that might be connected to spon...
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Article
Open AccessPANoptosis: a potential new target for programmed cell death in breast cancer treatment and prognosis
Breast cancer is a prevalent and severe form of cancer that affects women all over the world. The incidence and mortality of breast cancer continue to rise due to factors such as population growth and the agin...
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Article
Preconception or prenatal acceptance of SMN1 gene carrier screening and carrier rate of spinal muscular atrophy: a retrospective study in 18,818 reproductive age women in Wuhan area of China
Spinal muscular atrophy (SMA) is an autosomal recessive disorder mainly affecting the neuromuscular system, which seriously threatens the life and health of patients. But few studies have reported the acceptan...
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Article
Pain Management for Older Adults Across the Cognitive Trajectory
This review investigated current research on the relationship between chronic pain and cognitive performance, subjective cognitive decline, and dementia. In addition, we reviewed current research on pain manag...
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Article
Open AccessMESH1 knockdown triggers proliferation arrest through TAZ repression
All organisms are constantly exposed to various stresses, necessitating adaptive strategies for survival. In bacteria, the main stress-co** mechanism is the stringent response triggered by the accumulation o...
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Article
Open AccessThe regulation of ferroptosis by MESH1 through the activation of the integrative stress response
All organisms exposed to metabolic and environmental stresses have developed various stress adaptive strategies to maintain homeostasis. The main bacterial stress survival mechanism is the stringent response t...
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Article
Open AccessZinc transporter ZIP7 is a novel determinant of ferroptosis
Ferroptosis is a newly described form of regulated cell death triggered by oxidative stresses and characterized by extensive lipid peroxidation and membrane damages. The name of ferroptosis indicates that the ...
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Article
An improved calculation model for predicting the coefficient of restitution and maximum impact force of rockfalls
Rockfalls, which are a common natural hazard, collide and continuously bounce along slope surfaces during their movement; the coefficient of restitution (COR) and impact force are two important characteristic ...
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Article
Air pollution, demographic structure, and the current account: an extended life-cycle model
Air pollution has an important impact on both human health and sustainable economic development. The relationship of the current account, which is an important carrier of international economic activity, with ...
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Article
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis
Critical to the bacterial stringent response is the rapid relocation of resources from proliferation toward stress survival through the respective accumulation and degradation of (p)ppGpp by RelA and SpoT homo...
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Article
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism
Ferroptosis is a specialized iron-dependent cell death that is associated with lethal lipid peroxidation. Modulation of ferroptosis may have therapeutic potential since it has been implicated in various human ...
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Article
Open AccessCoA synthase regulates mitotic fidelity via CBP-mediated acetylation
The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here we present evidence that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransf...
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Article
Open AccessAcidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
A variety of oncogenic and environmental factors alter tumor metabolism to serve the distinct cellular biosynthetic and bioenergetic needs present during oncogenesis. Extracellular acidosis is a common microen...
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Article
Open AccessAntagonistic, overlap** and distinct responses to biotic stress in rice (Oryza sativa) and interactions with abiotic stress
Every year, substantial crop loss occurs globally, as a result of bacterial, fungal, parasite and viral infections in rice. Here, we present an in-depth investigation of the transcriptomic response to infectio...
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Article
Open AccessEffect of Jiaji electroacupuncture in transected rat spinal cord
We evaluated the effect of Jiaji electroacupuncture on cell proliferation and the expression of markers of endogenous neural stem cell activation after complete spinal cord transection. Female Wistar rats were...
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Article
Genetic analysis and gene map** of a new rolled-leaf mutant in rice (Oryza sativa L.)
To understand the development of rice leaf blades, we identified a new rolled-leaf mutant, w32, from indica cultivar IR64 through EMS mutagenesis. The mutant showed a stable rolled-leaf phenotype throughout th...
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Chapter and Conference Paper
What it Takes to Achieve Durable Resistance to Rice Blast?
Based on performance record, varieties with a reputation for possessing durable blast resistance can be identified from breeding programs. For most of these varieties, a combination of major resistance genes a...
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Chapter
Chemical- and Irradiation-Induced Mutants and TILLING
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Article
Genetic diversity and relatedness of selected Iranian rice cultivars and disease resistance donors assayed by simple sequence repeats and candidate defense gene markers
As a prerequisite to improving diseaseresistance and grain quality in Iranianrice cultivars, we determined the geneticrelatedness of popular local cultivars andblast-resistance donor germplasm usingfingerprint...
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Article
Importance of over-dominance as the genetic basis of heterosis in rice
In populations derived from commercial hybrid rice combination Shanyou 10, F1 heterosis and F2 inbreeding depression were observed on grain yield (GYD) and number of panicles (NP). Using marker loci evenly distri...
