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Article
METTL3 regulatory TROAP can regulate the progression of non-small cell lung cancer through PI3K/AKT and EMT signaling pathway
TROAP, interacts with trophinin and bystin, polys a key role in embryo implantation. TROAP is required for spindle assembly and centrosome integrity during the mitosis. TROAP has been described to promote tumo...
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Article
Open AccessCorrection to: HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine
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Spatio-temporal keyword query in semantic trajectories
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Open AccessHLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine
CD8+ T cell-mediated adaptive cellular immunity and natural killer (NK) cell-mediated innate immunity both play important roles in tumour immunity. This study aimed to develop therapeutic tumour vaccines based on...
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Article
Open AccessCell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer
TMEM16A (known as anoctamin 1) Ca2+-activated chloride channel is overexpressed in many tumors. TMEM16A overexpression can be caused by gene amplification in many tumors harboring 11q13 amplification. TMEM16A exp...
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Article
Assessment of HCV genotypes in Yunnan Province of Southwest China
Recently, we reported that the frequency of hepatitis C virus (HCV) genotypes and subtypes has rapidly changed among intravenous drug users (IDUs) in Yunnan Province over the last 5 years; this is especially t...
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Article
Effect of La2O3 addition on the microwave dielectric properties of Ba(Mg1/3Ta2/3)O3 ceramics
In this paper, Ba(Mg1/3Ta2/3)O3 (BMT) ceramics with x (x = 0–5) wt% La2O3 were prepared by the conventional solid-state ceramic route for investigating the effect of La2O3 addition on the microwave dielectric pro...
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Article
Open AccessSingle Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian
An effective cytotoxic immune response to neoplastic cells requires efficient presentation of antigenic peptides to T lymphocytes by HLA class I (HLA-I) molecules. The HLA-I-bound peptide repertoire depends on...
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Article
Association and differentiation of MHC class I and II polymorphic Alu insertions and HLA-A, -B, -C and -DRB1 alleles in the Chinese Han population
In order to investigate the polymorphism of Alu insertions (POALINs) in the HLA region, we genotyped ten Alu loci (AluMICB, AluTF, AluHJ, AluHG, AluHF in the HLA class I region and AluDPB2, AluDQA2, AluDQA1, A...
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Research on Parallelizing Trie-Based Apriori Algorithm
In order to improve the Trie-based Apriori, this paper introduces a parallel scheme. On the basis of Trie’s properties, the computation tasks will execute concurrently from single computer to multiple computer...
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Article
Multiple origins of Tibetan Y chromosomes
The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two do...
