23 Result(s)

Article

Plasma Epstein-Barr virus microRNA BART8-3p as a potential biomarker for detection and prognostic prediction in early nasopharyngeal carcinoma

Epstein-Barr virus (EBV) encoded microRNA BART8-3p (miR-BART8-3p) was significantly associated with the metastasis in nasopharyngeal carcinoma (NPC). To explore the clinical values of plasma miR-BART8-3p in pa...

Cheng Lin, Yuebing Chen, **andong Lin, Hewei Peng, Juan Huang… in Scientific Reports (2024)

Article

Risk-adapted locoregional radiotherapy strategies based on a prognostic nomogram for de novo metastatic nasopharyngeal carcinoma patients treated with chemoimmunotherapy

To develop a prognostic nomogram for individualized strategies on locoregional radiation therapy (LRRT) in patients with de novo metastatic nasopharyngeal carcinoma (dmNPC) treated with chemoimmunotherapy. Nin...

Yuebing Chen, Chuying Chen, Hewei Peng, Shaojun Lin, Jianji Pan… in Scientific Reports (2024)

Article

Identification of an individualized therapy prognostic signature for head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) are the most common cancers in the head and neck. Therapeutic response-related genes (TRRGs) are closely associated with carcinogenesis and prognosis in HNSCC. How...

Cheng Lin, Yuebing Chen, Jianji Pan, Qiongjiao Lu, Pengjie Ji, Shuiqin Lin… in BMC Genomics (2023)

Article

Stereotactic body radiotherapy extends the clinical benefit of PD-1 inhibitors in refractory recurrent/metastatic nasopharyngeal carcinoma

Emerging evidence shows that immune checkpoint inhibitors lead to durable responses in a variety of cancers, including nasopharyngeal carcinoma (NPC), however, combination approaches (i.e., stereotactic body r...

**g Lin, Qiaojuan Guo, Zengqing Guo, Tianzhu Lu, Gang Chen… in Radiation Oncology (2022)

Article

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma

Accumulated evidence suggests that RING finger proteins (RNFs) are involved in the carcinogenesis of cancers. However, RNF38, a member of the RNF protein family, has not been studied in nasopharyngeal carcinom...

Cheng Lin, Meifang Li, Na Lin, **gfeng Zong, Jianji Pan, Yunbin Ye in BMC Cancer (2022)

Article

Optimizing the treatment mode for de novo metastatic nasopharyngeal carcinoma with bone-only metastasis

No standard radiotherapy regimens have been established for the treatment of de novo metastatic nasopharyngeal carcinoma (mNPC) with bone-only metastasis. The current study aimed to investigate the efficacy of...

Cheng Lin, Sheng Lin, Lili Zhu, Shaojun Lin, Jianji Pan, Yun Xu in BMC Cancer (2022)

Article

Publisher Correction: Toripalimab or placebo plus chemotherapy as first-line treatment in advanced nasopharyngeal carcinoma: a multicenter randomized phase 3 trial

Hai-Qiang Mai, Qiu-Yan Chen, Dong** Chen, Chaosu Hu, Kunyu Yang… in Nature Medicine (2022)

Article

Maintenance chemotherapy using S-1 following definitive chemoradiotherapy in patients with N3 nasopharyngeal carcinoma

Patients with N3 stage nasopharyngeal carcinoma (NPC) are at high risk for treatment failure. This study aims to assess the efficacy of maintenance chemotherapy (MC) using S-1 (MC-S1), a novel oral fluoropyrim...

**gfeng Zong, Hanchuan Xu, Bijuan Chen, Qiaojuan Guo, Yun Xu… in Radiation Oncology (2019)

Article

Correction to: EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways

Following publication of the original article [1], the authors reported two errors in the article. In the caption of Figure 1c the sentence “The 20 most highly upregulated EBV BART miRNAs identified between NP...

Cheng Lin, **gfeng Zong, Wansong Lin… in Journal of Experimental & Clinical Cancer … (2019)

Article

EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways

Epstein-Barr virus (EBV) is ubiquitously associated with nasopharyngeal carcinoma (NPC). EBV encodes two groups of microRNAs (miRNAs) which are divided into BamHI fragment H rightward open reading frame 1 (BHRF1)...

Cheng Lin, **gfeng Zong, Wansong Lin… in Journal of Experimental & Clinical Cancer … (2018)

Article

Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

Distant metastasis is the primary failure pattern of nasopharyngeal carcinoma(NPC) in intensity-modulated radiation therapy(IMRT) era. This study was conducted to find the impact of genetic variations in the p...

Qiaojuan Guo, Tianzhu Lu, Yan Chen, Ying Su, Yuhong Zheng, Zeng Chen… in Scientific Reports (2016)

Article

Prognostic value of MRI-derived masticator space involvement in IMRT-treated nasopharyngeal carcinoma patients

This retrospective study reassessed nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiation therapy (IMRT), to determine the significance how magnetic resonance imaging (MRI)-derived...

Jianji Pan, Yunbin Chen, Shaojun Lin, Ying Chen… in Radiation Oncology (2015)

Article

Cervical lymph node metastasis classified as regional nodal staging in thoracic esophageal squamous cell carcinoma after radical esophagectomy and three-field lymph node dissection

Lymph node metastasis (LNM) is most common in esophageal squamous cell carcinoma (SCC). The bi-directional spread is a key feature of LNM in patients with thoracic esophageal SCC (TE-SCC). The purpose of this ...

Junqiang Chen, Sangang Wu, **ongwei Zheng, Jianji Pan, Kunshou Zhu… in BMC Surgery (2014)

Article

Advantages of intensity modulated radiotherapy in recurrent T1-2 nasopharyngeal carcinoma: a retrospective study

Recurrent T1-2 Nasopharyngeal Carcinoma (rT1-2) may be salvaged by 3D – CRT (3D-Conformal Radiotherapy), IMRT (Intensity Modulated Radiotherapy), Brachytherapy (BT), BT with external radiotherapy. The purpose ...

Sufang Qiu, Jun Lu, Wei Zheng, Luying Xu, Shaojun Lin, Chaobin Huang… in BMC Cancer (2014)

Article

Label-free blood plasma test based on surface-enhanced Raman scattering for tumor stages detection in nasopharyngeal cancer

This study aims to evaluate the feasibility of a label-free nanobiosensor based on blood plasma surface-enhanced Raman spectroscopy (SERS) method for exploring variability of different tumor (T) stages in naso...

Duo Lin, Jianji Pan, Hao Huang, Guannan Chen, Sufang Qiu, Hong Shi… in Scientific Reports (2014)

Article

Survival analyses correlate stanniocalcin 2 overexpression to poor prognosis of nasopharyngeal carcinomas

Stanniocalcin 2 (STC2) is overexpressed in several types of human cancers, and its overexpression positively correlates to tumor progression and poor prognosis. However, the clinical significance of STC2 overe...

Shaojun Lin, Qiaojuan Guo, Jiangmei Wen… in Journal of Experimental & Clinical Cancer … (2014)

Article

Radiation therapy for locoregionally advanced nasopharyngeal carcinoma in elderly patients

The aim of this study was to evaluate the treatment outcome and toxicities of radiation therapy alone for elderly patients with locoregionally advanced nasopharyngeal carcinoma (NPC).

Qiaojuan Guo, Wei** Jiang, Shaojun Lin, Ling Yang… in Journal of Radiation Oncology (2012)