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  1. Article

    Open Access

    Relationship between preoperative high triglyceride-glucose index and myocardial injury following non-cardiac surgery in advanced-age patients: a retrospective cohort study

    Myocardial injury after non-cardiac surgery (MINS) is a common and insidious postoperative complication. This study aimed to evaluate the relationship between the triglyceride-glucose index (TyG) and MINS in a...

    Siyi Yao, Kai Zhang, Yu Yang, Zhao Li, Chang Liu in Diabetology & Metabolic Syndrome (2024)

  2. Article

    Open Access

    Correction: Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study

    Miao Sun, Min Liu, Faqiang Zhang, Lijuan Sang, Yuxiang Song in Lipids in Health and Disease (2024)

  3. Article

    Open Access

    Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study

    Postoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker...

    Miao Sun, Min Liu, Faqiang Zhang, Lijuan Sang, Yuxiang Song in Lipids in Health and Disease (2024)

  4. Article

    Open Access

    The relationship between trajectories of renal oxygen saturation and acute kidney injury: a prospective cohort study with a secondary analysis

    Acute kidney injury (AKI) is a major postoperative consequence, affecting prognosis of older patients. Effective prediction or intervention to predict or prevent the incidence of AKI is currently unavailable.

    Chang Liu, **aoxiao Wang, Wenzhu Shi, Yao Yu in Aging Clinical and Experimental Research (2024)

  5. Article

    Open Access

    Prediction models for postoperative delirium in elderly patients with machine-learning algorithms and SHapley Additive exPlanations

    Postoperative delirium (POD) is a common and severe complication in elderly patients with hip fractures. Identifying high-risk patients with POD can help improve the outcome of patients with hip fractures. We ...

    Yuxiang Song, Di Zhang, Qian Wang, Yuqing Liu, Kunsha Chen in Translational Psychiatry (2024)

  6. Article

    Open Access

    Association between intraoperative mean arterial pressure variability and postoperative delirium after hip fracture surgery: a retrospective cohort study

    Postoperative delirium (POD) is a common complication in elderly patients after hip fracture surgery. Our study was to investigate whether intraoperative mean arterial pressure variability (MAPV) was associate...

    Chuangxin Zhang, Yuxiang Song, **aodong Wu, Ran Miao, **gsheng Lou in BMC Geriatrics (2023)

  7. Article

    Open Access

    The modified lymphocyte C-reactive protein score is a promising indicator for predicting 3-year mortality in elderly patients with intertrochanteric fractures

    Hip fractures are common in elderly patients, and almost all the patients undergo surgery. This study aimed to develop a novel modified lymphocyte C-reactive protein (CRP) score (mLCS) to simply and convenient...

    Zile He, Chuangxin Zhang, Mingzi Ran, **n Deng, Zilin Wang, Yanhong Liu in BMC Geriatrics (2023)

  8. Article

    Open Access

    Systemic immune-inflammation index predicts postoperative delirium in elderly patients after surgery: a retrospective cohort study

    Postoperative delirium (POD) is a common complication among elderly patients after surgery. It is unclear whether the systemic immune-inflammation index (SII) can be a predictor of POD. We explored the prognos...

    Yuxiang Song, Yungen Luo, Faqiang Zhang, Yulong Ma, **gsheng Lou, Hao Li in BMC Geriatrics (2022)

  9. No Access

    Article

    Dopaminergic Neurons in the Ventral Tegmental–Prelimbic Pathway Promote the Emergence of Rats from Sevoflurane Anesthesia

    Dopaminergic neurons in the ventral tegmental area (VTA) play an important role in cognition, emergence from anesthesia, reward, and aversion, and their projection to the cortex is a crucial part of the "botto...

    Yan** Song, Ruitong Chu, Fuyang Cao, Yanfeng Wang, Yanhong Liu in Neuroscience Bulletin (2022)

  10. Article

    Open Access

    Comparison of propofol-nalbuphine and propofol-fentanyl sedation for patients undergoing endoscopic retrograde cholangiopancreatography: a double-blind, randomized controlled trial

    Endoscopic retrograde cholangiopancreatography (ERCP) has been increasingly used to treat patients with biliary/pancreatic duct obstruction or stricture outside the operating room. Effective and safe sedation ...

    Peiqi Wang, Yan Chen, Ying Guo, Jiangbei Cao, Hong Wang, Weidong Mi in BMC Anesthesiology (2022)

  11. Article

    Open Access

    Development and validation of a risk nomogram for postoperative acute kidney injury in older patients undergoing liver resection: a pilot study

    Postoperative acute kidney injury (AKI) is associated with poor clinical outcomes. Early identification of high-risk patients of develo** postoperative AKI can optimize perioperative renal management and fac...

    Yao Yu, Changsheng Zhang, Faqiang Zhang, Chang Liu, Hao Li in BMC Anesthesiology (2022)

  12. Article

    Open Access

    LMA® protector™ in patients undergoing laparoscopic surgeries: a multicenter prospective observational study

    Laryngeal masks airway (LMA) has been increasingly used in surgical patients. However, the use of LMA in laparoscopic surgeries remains controversial. The major concerns include the potential risk of esophagea...

    Yanhong Liu, Yuxiang Song, Miaomiao Wang, Meihua Yang, Hao Shen in BMC Anesthesiology (2021)

  13. Article

    Open Access

    Cottonseed oil alleviates ischemic stroke injury by inhibiting the inflammatory activation of microglia and astrocyte

    Ischemic stroke is the second leading cause of death globally. The narrow time window for administering effective thrombolytic therapy motivates the search for alternative prevention strategies. Microglia and ...

    Min Liu, Zhipeng Xu, Long Wang, Lixia Zhang, Yi Liu in Journal of Neuroinflammation (2020)

  14. Article

    Open Access

    Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

    It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolys...

    Weixing Zhao, Zhipeng Xu, Jiangbei Cao, Qiang Fu in Journal of Neuroinflammation (2019)

  15. Article

    Open Access

    MiR-190a potentially ameliorates postoperative cognitive dysfunction by regulating Tiam1

    Postoperative cognitive dysfunction (POCD) affects a large number of post-surgery patients, especially for the elderly. However, the etiology of this neurocognitive disorder is largely unknown. Even if several...

    Qiang Liu, Aisheng Hou, Yongyi Zhang, Ying Guo, **g**g Li, Yinghao Yao in BMC Genomics (2019)

  16. Article

    Open Access

    Critical role of inflammatory cytokines in impairing biochemical processes for learning and memory after surgery in rats

    Patients with postoperative cognitive dysfunction have poor outcomes. Neuroinflammation may be the underlying pathophysiology for this dysfunction. We determined whether proinflammatory cytokines affect the tr...

    Hongying Tan, Jiangbei Cao, Junfeng Zhang, Zhiyi Zuo in Journal of Neuroinflammation (2014)