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Article
Open AccessNEK2 affects the ferroptosis sensitivity of gastric cancer cells by regulating the expression of HMOX1 through Keap1/Nrf2
NEK2 is a serine/threonine protein kinase that is involved in regulating the progression of various tumors. Our previous studies have found that NEK2 is highly expressed in gastric cancer and suggests that pat...
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Article
Open AccessIdentification and characterization of circular RNAs involved in the fertility stability of cotton CMS-D2 restorer line under heat stress
As a vital type of noncoding RNAs, circular RNAs (circRNAs) play important roles in plant growth and development and stress response. However, little is known about the biological roles of circRNAs in regulati...
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Article
Open AccessHeat-responsive microRNAs participate in regulating the pollen fertility stability of CMS-D2 restorer line under high-temperature stress
Anther development and pollen fertility of cytoplasmic male sterility (CMS) conditioned by Gossypium harknessii cytoplasm (CMS-D2) restorer lines are susceptible to continuous high-temperature (HT) stress in sum...
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Article
Open AccessGenome-wide identification of the geranylgeranyl pyrophosphate synthase (GGPS) gene family involved in chlorophyll synthesis in cotton
Geranylgeranyl pyrophosphate synthase (GGPS) is a structural enzyme of the terpene biosynthesis pathway that is involved in regulating plant photosynthesis, growth and development, but this gene family has not...
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Article
Open AccessProgress and perspective on cotton breeding in Pakistan
Cotton is the prime natural fiber with economic significance globally. Cotton farming and breeding have a long history in Pakistan. The development of high yielding upland cotton (Gossypium hirsutum) varieties gr...
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Article
Open AccessConservation status of threatened land plants in China and priority sites for better conservation targets: distribution patterns and conservation gap analysis
There are about 10% of the world’s land plants in China, of which 11% are threatened species. Here, we used China as a proxy to identify hotspots of threatened species, evaluate the effectiveness of current co...
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Article
Open AccessComparative performance of hybrid generations reveals the potential application of F2 hybrids in upland cotton
The utilization of heterosis has greatly improved the productivity of cotton worldwide. However, a major constraint for the large-scale promotion of F1 hybrid cotton is artificial emasculation and pollination. Th...
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Article
Open AccessAcute health effects associated with satellite-determined cyanobacterial blooms in a drinking water source in Massachusetts
The occurrence of cyanobacterial blooms in freshwater presents a threat to human health. However, epidemiological studies on the association between cyanobacterial blooms in drinking water sources and human he...
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Article
Open AccessInduction therapy with mesenchymal stromal cells in kidney transplantation: a meta-analysis
The aim of this meta-analysis was to evaluate the therapeutic effects of mesenchymal stromal cells (MSCs) versus traditional regimens for induction therapy in kidney transplantation (KT), especially the safety...
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Article
Open AccessPhysical map** and InDel marker development for the restorer gene Rf2 in cytoplasmic male sterile CMS-D8 cotton
Cytoplasmic male sterile (CMS) with cytoplasm from Gossypium Trilobum (D8) fails to produce functional pollen. It is useful for commercial hybrid cotton seed production. The restore line of CMS-D8 containing Rf2 ...
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Article
Open AccessComparative transcriptome analysis between inbred and hybrids reveals molecular insights into yield heterosis of upland cotton
Utilization of heterosis has greatly improved the productivity of many crops worldwide. Understanding the potential molecular mechanism about how hybridization produces superior yield in upland cotton is criti...
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Article
Open AccessComparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton
Heterosis breeding is the most useful method for yield increase around the globe. Heterosis is an intriguing process to develop superior offspring to either parent in the desired character. The biomass vigor p...
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Open AccessGenetic analysis of yield and fiber quality traits in upland cotton (Gossypium hirsutum L.) cultivated in different ecological regions of China
Cotton is an important fiber crop worldwide. The yield potential of current genotypes of cotton can be exploited through hybridization. However, to develop superior hybrids with high yield and fiber quality tr...
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Article
Open AccessPrevalence of Zika virus in blood donations: a systematic review and meta-analysis
Transfusion-Transmitted Zika virus (TT-ZIKV) has become an emerging threat to world blood banks due to the fast spread of ZIKV epidemics and high rate of asymptomatic infections. For the risk assessment of ZIK...
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Article
Open AccessCorrection to: Genome-wide analysis of Rf-PPR-like (RFL) genes and a new InDel marker development for Rf1 gene in cytoplasmic male sterile CMS-D2 Upland cotton
In the original publication of this article (Zhang et al. 2018) the first name and surname of the eighth author are in reverse order. The correct name of the eighth author should be SHAHZAD Kashif. In ‘Authors...
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Article
Open AccessGenome-wide analysis of Rf-PPR-like (RFL) genes and a new InDel marker development for Rf1 gene in cytoplasmic male sterile CMS-D2 Upland cotton
Cytoplasmic male sterility in flowering plants is a convenient way to use heterosis via hybrid breeding and may be restored by nuclear restorer-of-fertility (Rf) genes. In most cases, Rf genes encoded pentatricop...
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Article
Open AccessA combined small RNA and transcriptome sequencing analysis reveal regulatory roles of miRNAs during anther development of Upland cotton carrying cytoplasmic male sterile Gossypium harknessii (D2) cytoplasm
Cytoplasmic male sterility (CMS) in flowering plants is usually caused by incompatibility between mitochondrial and nuclear genomes, and can be restored by nuclear genes known as restorer-of-fertility (Rf). Altho...
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Article
Open AccessSalvianolic acid B inhibits glycolysis in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1α signaling pathway
Our previous study demonstrated a progressive glycolytic perturbation during the course of DMBA-induced hamster oral carcinogenesis, which was attenuated by salvianolic acid B (Sal-B) treatment along with decr...
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Article
Open AccessSpatial and Temporal Characteristics of 2014 Dengue Outbreak in Guangdong, China
The record-breaking number of dengue cases reported in Guangdong, China in 2014 has been topic for many studies. However, the spatial and temporal characteristics of this unexpectedly explosive outbreak are st...
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Article
Open AccessErratum: Uricase alkaline enzymosomes with enhanced stabilities and anti-hyperuricemia effects induced by favorable microenvironmental changes
Scientific Reports 6: Article number: 20136; published online: 29 January 2016; updated: 30 June 2017. The original HTML version of this Article listed an incorrect volume number. This has now been corrected i...
