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Article
Open AccessMetformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation
Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients develo** polycystic kidney disease and leading to a decline of renal function. TSC is caused ...
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Article
Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential
Diabetic kidney disease, a leading cause of end-stage renal disease, has become a serious public health problem worldwide and lacks effective therapies. Autophagy is a highly conserved lysosomal degradation pa...
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Article
CHAUS: Scalable VM-Based Channels for Unbounded Streaming
Stream processing is a special form of the dataflow execution model that offers extensive opportunities for optimization and automatic parallelism. A streaming application is represented by a graph of computat...
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Article
In-vivo investigation of laser-induced choroidal neovascularization in rat using spectral-domain optical coherence tomography (SD-OCT)
This study investigated the in-vivo formation process of laser-induced choroidal neovascularization (CNV) in rat using high-resolution spectral-domain optical coherence tomography (SD-OCT), and compared the re...
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Chapter and Conference Paper
A Constitutive Model of a Particle Reinforced Viscoelastic Composite Material with Debonded Microvoids
The statistical behavior of microvoids’ evolution in a linear viscoelastic material which contains well bonded second phase particles is investigated. The particle size distribution is assumed to obey a logari...
