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Article
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBi**g, a Chinese herb-based intravenous formulation
Sepsis, a life-threatening health issue, lacks effective medicine targeting the septic response. In China, treatment combining the intravenous herbal medicine XueBi**g with conventional procedures reduces the...
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Article
Numerical simulation of nozzle structure to improve eccentric mold electromagnetic stirring in a round bloom mold
A three-dimensional mathematical model coupling electromagnetic, flow, heat transfer, and solidification has been developed to investigate the effect of eccentric mold electromagnetic stirring (EM-EMS) on the ...
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Article
Waveguide distribution system of the HEPS linac
The High-Energy Photon Source (HEPS) is a 6 GeV storage ring-based light source under construction in Bei**g, China. Its accelerator consists of a 6 GeV storage ring, a full-energy booster, an S-band normal-c...
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Article
A review of research on central crack in continuous casting strand
Central crack is a common quality defect in continuous casting strand, which is difficult to fully weld in the rolling and forging processes, and has become a key technical problem that restricts the stable pr...
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Article
Seasonal flexibility of the gut structure and physiology in Eremias multiocellata
Although gut seasonal plasticity has been extensively reported, studies on physiological flexibility, such as water-salt transportation and motility in reptiles, are limited. Therefore, this study investigated...
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Article
Cursor control through hand shape and Z dimension movements to assist target acquisition in large displays
This study investigated a “hand cursor” technique which used an open hand to control an area cursor (i.e., a cursor with a larger active area) while using an index finger extended gesture to switch the area cu...
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Chapter and Conference Paper
Recognition of Sedimentary Model and Fine Characterization Technology of Huge Thick Glutenite Fan in the Steep Slope Zone of the Bohai Bay
The A oilfield in the Bohai bay is a near-source glutenite fan delta lithologic structural reservoir that has been discovered in the steep slope zone at the edge of the bulge area. The reservoir of A oilfiled ...
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Article
Open AccessFive-year remission without disease progression in a patient with relapsed/refractory multiple myeloma with extramedullary disease treated with LCAR-B38M chimeric antigen receptor T cells in the LEGEND-2 study: a case report
Multiple myeloma remains incurable despite treatment advancements over the last 20 years. LCAR-B38M Cells in Treating Relapsed/Refractory Multiple Myeloma was a phase 1, first-in-human, investigator-initiated ...
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Article
Effect of CaCO3 on volatilization of self-reduced zinc from blast furnace dust
To solve the problem of low reduction extraction rate of zinc from blast furnace dust, the effects of CaCO3 addition, reduction temperature, and reduction time on self-reduction zinc extraction were studied throu...
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Article
Open AccessFour-year follow-up of LCAR-B38M in relapsed or refractory multiple myeloma: a phase 1, single-arm, open-label, multicenter study in China (LEGEND-2)
LCAR-B38M is a chimeric antigen receptor T cell product with two binding domains targeting B cell maturation antigen. Our previous reports showed a remarkable efficacy of LCAR-B38M in patients with relapsed/re...
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Chapter and Conference Paper
Study on the Research Progress and Development Trend of Refracturing Technique in Shale Gas Reservoirs
Refracturing technique is a promising means to improve the output and estimated ultimate recovery of shale oil and gas resources, which is an efficient method to recover the productivity of low permeability ol...
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Article
High-accuracy electrohydraulic control system for the position and orientation of the primary mirror for a large telescope
Due to variations in gravity, temperature, and external disturbances, the optical axes of a telescope’s primary mirrors can shift and, consequently, become misaligned with the light path. Such misalignment sig...
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Article
Commissioning experiences with the spoke-based CW superconducting proton linac
The 10-MeV Accelerator-Driven Subcritical (ADS) system Injector-I test stand at the Institute of High Energy Physics (IHEP) is a testing facility dedicated to demonstrating the feasibility of the spoke-based s...
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Article
Open AccessComprehensive analysis of the transcriptional expressions and prognostic value of S100A family in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory malignancy with poor prognosis. It is urgent to identify novel and valid biomarkers to predict the progress and prognosis of PDAC. The S10...
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Article
Flatness Measurement of a Mosaic Focal Plane by using a Coaxial Multispectral Laser
The wide-field telescope will be an important tool in the discovery and birth of new theories of astronomy in future. The detectors in this kind of telescope mostly adopt a mosaic focal plane array. The focal ...
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Article
Open AccessThe relationship between depression risk perception and self-help behaviours in high risk Canadians: a cross-sectional study
Self-help may reduce the risk of depression, and risk perception of depression may influence initiating self-help. It is unknown how risk perception is associated with self-help behaviours. The objectives of t...
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Article
Association between hydrogen sulfide and OSA-associated hypertension: a clinical study
We sought to unravel the role of hydrogen sulfide (H2S) in the development of hypertension in patients with obstructive sleep apnea (OSA).
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Article
Fiber Positioner Based on Flexible Hinges Amplification Mechanism
Due to the nonlinear effect and the thermal effect, a single optical fiber has limitations in the output power. A beam combination of laser arrays based on adaptive optics can both improve the output power and...
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Article
Open AccessA phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell therapy directe...
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Article
Open AccessYouth at-risk for serious mental illness: methods of the PROCAN study
Most mental disorders begin in adolescence; however, there are gaps in our understanding of youth mental health. Clinical and policy gaps arise from our current inability to predict, from amongst all youth who...
