Geotechnical Reliability Analysis
Theories, Methods and Algorithms
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Article
Probabilistic and physically-based modelling of rainfall-induced landslide susceptibility using integrated GIS-FORM algorithm
The susceptibility map** of rainfall-induced landslides is an effective tool for predicting and locating disaster-prone zones at the regional scale. One of the most important parts of landslide susceptibilit...
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Investigation of seismic displacements in bedding rock slopes by an extended Newmark sliding block model
Earthquake-induced plane failure is typically generated on bedding rock slopes. This failure mode has been widely observed in the past earthquakes in Western China (e.g., Wenchuan earthquake). Among them, the ...
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Article
Uncertainty evaluation of the run-out distance of flow-like landslides considering the anisotropic scale of fluctuation in the random field of internal friction angle
Naturally, sedimented strata bring about complicated distributions for geomaterial properties with different random field parameters in different directions, e.g., the anisotropic scale of fluctuation (SOF). T...
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Article
A Modified Model for Soil-Structure Interface Considering Random Damage of Mesoscopic Contact Elements
The interaction between soil and marine structures like submarine pipeline/pipe pile/suction caisson is a complicated geotechnical mechanism process. In this study, the interface is discretized into multiple m...
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Article
Open AccessComprehensive analysis of m6A regulators and relationship with tumor microenvironment, immunotherapy strategies in colorectal adenocarcinoma
The N6-methyladenosine (m6A) RNA modification is the most prevalent and abundant type found in eukaryotic cells. It plays a crucial role in the initiation and progression of cancers. In this study, we aimed to...
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Article
PCSK9 Inhibition Regulates Infarction-Induced Cardiac Myofibroblast Transdifferentiation via Notch1 Signaling
Increasing evidence suggests that PCSK9 inhibition protects cardiomyocytes against ischemia-reperfusion injury after myocardial infarction. However, it is not clear whether PCSK9 inhibitor (PCSK9i) affects car...
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Article
Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences
Systematically identifying functional peptides is difficult owing to the vast combinatorial space of peptide sequences. Here we report a machine-learning pipeline that mines the hundreds of billions of sequenc...
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Article
Upper bound seismic limit analysis of shallow landslides with a new kinematically admissible failure mechanism
Many landslides are shallow and earthquake is one of the common triggering factors. This study presents upper bound seismic limit analysis of shallow landslides with a novel kinematically admissible translatio...
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Article
Open AccessIn vivo bioluminescence imaging of natural bacteria within deep tissues via ATP-binding cassette sugar transporter
Most existing bioluminescence imaging methods can only visualize the location of engineered bacteria in vivo, generally precluding the imaging of natural bacteria. Herein, we leverage bacteria-specific ATP-bin...
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Article
UV-triggered Polymerization of Polyelectrolyte Composite Coating with Pore Formation and Lubricant Infusion
Porous coatings with the features of muti-interfaces and high specific surface area have emerged as an excellent material platform for the manipulation of porous structures. Layer-by-layer (LbL) assembly techn...
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Chapter
Spatial Variability of Soils
Due to the complex geologic, environmental, and physical–chemical processes, geotechnical properties vary spatially even in the same geological unit, referred to as spatial variability.
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Chapter
Bayesian Methods
The uncertainty in geotechnical engineering depends on the amount of information available. When more information is available, such information can be used to reduce the uncertainty in geotechnical engineerin...
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Book
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Chapter
First Order Reliability Methods
Due to the existence of uncertainties in geotechnical engineering, the performance of a geotechnical system can hardly be predicted deterministically. In such a case, the performance of a geotechnical system c...
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Chapter
Response Surface Methods
The RSMs are a set of techniques used in the empirical study of relationships [1]. It was proposed by Box and Wilson in 1951 [2], and it is currently widely used in reliability analysis.
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Chapter
Reliability-Based Design
The working stress design has long been used in civil engineering (e.g., Barker et al. in Manuals for the design of bridge foundations: shallow foundations, driven piles, retaining walls and abutments, drilled...
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Chapter
Basics of Probability Theory
Uncertainties are pervasive in geotechnical engineering, such as the inherent variability of the soil, the measurement error due to imperfect testing, the statistical uncertainties due to limited amount of tes...
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Chapter
Simulation-Based Methods
Although first-order reliability methods introduced in the previous chapter are efficient and easy to apply, they may not work well for problems with high dimensionality, nonlinear performance functions, and m...
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Article
Closed-form solutions for regional earthquake–induced landslide prediction: rotational failure mechanism
Seismic slope stability analysis at regional scale (e.g., landslide hazard map**, infrastructure slope management) is essential in areas that are susceptible to earthquake. Analytical infinite slope model is...
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Article
An ROS-Responsive Antioxidative Macromolecular Prodrug of Caffeate for Uveitis Treatment
Uveitis is a sophisticated syndrome showing a high relevance with reactive oxygen species (ROS). Herein, an ROS-responsive PEGylated polypeptide based macromolecular prodrug of herbaceous antioxidant ethyl caf...
