179 Result(s)

Article

The detection of nuclear matrix in most primitive present- existing eukaryote, Giardia lamblia

The nuclear matrix of diplomonad Giardia lambBa was detected for the first time with DGD embedment-sectioning-embedment free electron microscopy after a series of specific extractions. The result showed that a...

Jialing Dai, **gyan Li, Siqi Lu in Cell Research (1995)

Article

Gene therapy for carcinoma of the breast: Pro-apoptotic gene therapy

The dysregulation of apoptosis contributes in a variety of ways to the malignant phenotype. It is increasingly recognized that the alteration of pro-apoptotic and anti-apoptotic molecules determines not only e...

Jesús Gómez-Navarro, Waleed Arafat, Jialing **ang in Breast Cancer Research (2000)

Article

Up-regulation of interferon-a/APOBEC3G signal pathway potently inactivates HIV-1 infectivity in resting CD4-T cells

Keyang Chen, Jialing Huang, Chune Zhang, Sophia Huang, Giuseppe Nunnari… in Retrovirology (2006)

Article

Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes

Permeabilization of the outer mitochondrial membrane is the point of no return in most programmed cell deaths. This critical step is mainly regulated by the various protein-protein and protein-membrane interac...

Brian Leber, Jialing Lin, David W. Andrews in Apoptosis (2007)

Article

Up-regulation of Bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen-independent growth stage

Bcl-2 is an anti-apoptotic oncoprotein and its protein levels are inversely correlated with prognosis in many cancers. However, the role of Bcl-2 in the progression of prostate cancer is not clear. Here we rep...

Yuting Lin, Junichi Fukuchi, Richard A Hiipakka, John M Kokontis… in Cell Research (2007)

Article

Proteasomal degradation unleashes the pro-death activity of androgen receptor

Androgen receptor (AR) is able to promote stress-induced cell death independently of its transcription activity in androgen-independent prostate cancer cells. Yet, the underlying mechanism is incompletely unde...

Bradley Godfrey, Yuting Lin, Jeffery Larson, Bonnie Haferkamp… in Cell Research (2010)

Article

Hyaluronan synthase mediates dye translocation across liposomal membranes

Hyaluronan (HA) is made at the plasma membrane and secreted into the extracellular medium or matrix by phospolipid-dependent hyaluronan synthase (HAS), which is active as a monomer. Since the mechanism by whic...

Andria P Medina, Jialing Lin, Paul H Weigel in BMC Biochemistry (2012)

Article

Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor

Traumatic brain injury (TBI) induces activation of microglia. Activated microglia can in turn increase secondary injury and impair recovery. This innate immune response requires hours to days to become fully m...

Joana C d’Avila, Tina I Lam, Deborah Bingham, Jian Shi… in Journal of Neuroinflammation (2012)

Article

The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system

Cerebral cortical neurons have a high vulnerability to the harmful effects of hypoxia. However, the brain has the ability to detect and accommodate to hypoxic conditions. This phenomenon, known as precondition...

Ramiro Echeverry, Fang Wu, Woldeab B Haile, Jialing Wu… in Journal of Neuroinflammation (2012)

Article

Genomic survey, expression profile and co-expression network analysis of OsWD40 family in rice

WD40 proteins represent a large family in eukaryotes, which have been involved in a broad spectrum of crucial functions. Systematic characterization and co-expression analysis of OsWD40 genes enable us to underst...

Yidan Ouyang, **aolong Huang, Zhanhua Lu, Jialing Yao in BMC Genomics (2012)

Article

Membrane-Based Continuous Remover of Trifluoroacetic Acid in Mobile Phase for LC-ESI-MS Analysis of Small Molecules and Proteins

We developed a “continuous” trifluoroacetic acid (TFA) remover based on electrodialysis with bipolar membrane for online coupling of liquid chromatography (LC) and electrospray ionization mass spectrometry (ES...

Zhigui Zhou, Jialing Zhang, … in Journal of The American Society for Mass S… (2012)

Article

Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats

Recurrent/moderate (R/M) hypoglycemia is common in type 1 diabetes. Although mild or moderate hypoglycemia is not life-threatening, if recurrent, it may cause cognitive impairment. In the present study, we sou...

Seok Joon Won, Byung Hoon Yoo, Tiina M Kauppinen… in Journal of Neuroinflammation (2012)

Article

Prevention of hypoglycemia-induced neuronal death by minocycline

Diabetic patients who attempt strict management of blood glucose levels frequently experience hypoglycemia. Severe and prolonged hypoglycemia causes neuronal death and cognitive impairment. There is no effecti...

Seok Joon Won, ** Hee Kim, Byung Hoon Yoo, Min Sohn… in Journal of Neuroinflammation (2012)

Article

Effects of exogenous enzymes and dietary energy on performance and digestive physiology of broilers

The study was conducted to compare the effects of XG with AG and BM at different metabolizable energy diets on growth performance, digestive physiology and energy utilization of broilers fed with corn-SBM diet...

Jialing Zou, ** Zheng, Keying Zhang… in Journal of Animal Science and Biotechnology (2013)

Article

The Chinese version of the pediatric quality of life inventory™ (PedsQL™) healthcare satisfaction generic module (version 3.0): psychometric evaluation

Healthcare satisfaction is an important indicator in quality of healthcare evaluations. Instruments with psychometric evaluation for pediatric healthcare satisfaction in China have been rarely studied. The Ped...

Jialing Li, Lianxiong Yuan, Yu Wu, Yunzhu Luan… in Health and Quality of Life Outcomes (2013)

Article

Combination therapy of anti-cancer bioactive peptide with Cisplatin decreases chemotherapy dosing and toxicity to improve the quality of life in xenograft nude mice bearing human gastric cancer

A great challenge of cancer chemotherapy is to eliminate cancer cells and concurrently maintain the quality of life (QOL) for cancer patients. Previously, we identified a novel anti-cancer bioactive peptide (A...

**ulan Su, Chao Dong, Jialing Zhang, Liya Su, Xuemei Wang, Hongwei Cui… in Cell & Bioscience (2014)

Article

Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

Influenza A viruses (IAVs), particularly H1N1, H5N1 and H7N9, pose a substantial threat to public health worldwide. Here, we report that MIR2911, a honeysuckle (HS)-encoded atypical microRNA, directly targets ...

Zhen Zhou, **han Li, **xiong Liu, Lei Dong, Qun Chen, Jialing Liu… in Cell Research (2015)

Article

A retrospective study of contributing factors for prognosis and survival length of cryptococcal meningoencephalitis in Southern part of China (1998–2013)

Cryptococcal meningoencephalitis (CM) is the most common opportunistic infection of the central nervous system (CNS). Despite this observation, there have only been a few studies analyzing clinical characteris...

Hui Zheng, Mingyue Li, Yingting Luo, Dongmei Wang, Jialing Yang… in BMC Infectious Diseases (2015)

Article

The mature anther-preferentially expressed genes are associated with pollen fertility, pollen germination and anther dehiscence in rice

The anthers and pollen grains are critical for male fertility and hybrid rice breeding. The development of rice mature anther and pollen consists of multiple continuous stages. However, molecular mechanisms re...

Sheng Ling, Caisheng Chen, Yang Wang, **aocong Sun, Zhanhua Lu… in BMC Genomics (2015)

Article

InbR, a TetR family regulator, binds with isoniazid and influences multidrug resistance in Mycobacterium bovis BCG

Isoniazid (INH), an anti-tuberculosis (TB) drug, has been widely used for nearly 60 years. However, the pathway through which Mycobacterium tuberculosis responds INH remain largely unclear. In this study, we char...

Min Yang, Chun-Hui Gao, Jialing Hu, Lei Zhao, Qiaoyun Huang… in Scientific Reports (2015)