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  1. Article

    Open Access

    NLRC5 promotes endometrial carcinoma progression by regulating NF-κB pathway-mediated mismatch repair gene deficiency

    The innate immune molecule NLR family CARD domain-containing 5 (NLRC5) plays a significant role in endometrial carcinoma (EC) immunosurveillance. However, NLRC5 also plays a protumor role in EC cells. Mismatch...

    **ao**g Liu, Haiqing Zhu, Bao Guo, Jiahua Chen, Junhui Zhang in Scientific Reports (2024)

  2. Article

    Open Access

    Identification of a serum-based microRNA signature that detects recurrent oral squamous cell carcinoma before it is clinically evident

    Survival rates for oral squamous cell carcinoma (OSCC) have remained poor for decades, a fact largely attributable to late-stage diagnoses and high recurrence rates. We report analysis of serum miRNA expressio...

    Rebecca Towle, Christopher T. D. Dickman, Sara A. MacLellan in British Journal of Cancer (2023)

  3. No Access

    Article

    A probabilistic dual hesitant fuzzy multi-attribute decision-making method based on entropy and cross-entropy

    The probabilistic dual hesitant fuzzy set (PDHFS), as an extension of generalization of the dual hesitant fuzzy set, contains not only the hesitation values of membership degree (MD) and non-membership degree ...

    **** Wang, Jiahua Chen in Granular Computing (2023)

  4. No Access

    Article

    Mixture of shifted binomial distributions for rating data

    Rating data are a kind of ordinal categorical data routinely collected in survey sampling. The response value in such applications is confined to a finite number of ordered categories. Due to population hetero...

    Shaoting Li, Jiahua Chen in Annals of the Institute of Statistical Mathematics (2023)

  5. Book Series

  6. No Access

    Chapter

    A Few Key Probability Theory Results

    The materials presented in this book are undeniably technical in nature. We established numerous theoretical conclusions by relying on classical probability theory results. Although these conclusions are well-...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  7. No Access

    Chapter

    Maximum Likelihood Estimation Under Finite Mixture Models

    Chapter 3 centers our attention on finite mixture models. Within this framework, we establish that the consistent results achieved with the maximum likelihood estimator for nonparametric mixture models remain ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  8. No Access

    Chapter

    Order Selection of the Finite Mixture Models

    The order selection problem, in contrast to determining whether a lower-ordered finite mixture model should be rejected in favor of a higher-ordered model, seeks to answer the question of what constitutes the ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  9. No Access

    Book

  10. No Access

    Chapter

    Geometric Properties of Non-parametric MLE and Numerical Solutions

    In Chap. 6, our attention turns to numerical solutions for maximum likelihood estimation within the context of nonparametric mixture models. The challenge arises from the infinite dimension of the nonparametri...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  11. No Access

    Chapter

    Rate of Convergence

    The fundamental requirement in data analysis is the consistent estimation of a parameter. As the sample size increases, the precision of the estimator naturally improves, following a rate of

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  12. No Access

    Chapter

    Modified Likelihood Ratio Test

    While achieving a profound understanding of the limiting distribution of the likelihood ratio test under mixture models is indeed a grand success, translating this knowledge into concrete data analysis procedu...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  13. No Access

    Chapter

    em-Test for Homogeneity

    The modified likelihood ratio test represents a significant advancement over the limitations of conventional likelihood ratio tests. It is applicable to a specific class of finite mixture models, although its ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  14. No Access

    Chapter

    em-Test for Univariate Finite Gaussian Mixture Models

    While the success of the EM-test in the previous two chapters was confined to finite mixture models with subpopulation distributions belonging to a one-parameter distribution family, the underlying principle o...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  15. No Access

    Chapter

    Introduction to Mixture Models

    In Chap. 1, we introduce the fundamental concept of a statistical model and provide a detailed definition of both mixture models and finite mixture models. We uncover the latent structure inherent in mixture m...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  16. No Access

    Chapter

    Consistent Estimation Under Finite Gamma Mixture

    The application of finite Gamma mixture models is prevalent when working with strictly positive observations. Surprisingly, the likelihood function within this framework is unbounded, theoretically leading to ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  17. No Access

    Chapter

    Finite Mixture MLE and EM Algorithm

    The latent structure inherent in mixture models offers a fitting scenario for the renowned EM algorithm. In Chap. 7, we begin by offering a general overview and then get into comprehensive explanations of the ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  18. No Access

    Chapter

    Test of Homogeneity

    The quest for effective tests of homogeneity within mixture models has a long history. An illustrative example provided by Hartigan shows that the likelihood ratio statistic, unlike its counterpart in regular ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  19. No Access

    Chapter

    Likelihood Ratio Test for Homogeneity

    Despite the successful application of the C( α \(\alpha \) ) test, statisticians continue to ...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

  20. No Access

    Chapter

    Modified Likelihood Ratio Test for Higher Order

    Chapter 12 centers around the modified likelihood test for high-order null hypotheses within the finite mixture model. While the fundamental concept of testing for high-order null hypotheses remains akin to th...

    Jiahua Chen in Statistical Inference Under Mixture Models (2023)

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