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  1. Article

    Open Access

    A pan-KRAS degrader for the treatment of KRAS-mutant cancers

    KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms of KRAS play a crucial role in driving cancer progression and conferring resistance to treatment. While there have bee...

    Jie Yang, Qiao-Li Wang, Guan-Nan Wang, Jia-Cong Ye, Zi-Qian Li… in Cell Discovery (2024)

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    Article

    Integrin α6-Targeted Magnetic Resonance Imaging of Hepatocellular Carcinoma in Mice

    Magnetic resonance imaging (MRI) has a high spatial resolution for detecting hepatocellular carcinoma (HCC). Integrin α6 has emerged as a diagnostic and prognostic biomarker of HCC. Here, we developed the MR c...

    Yun Zhang, **g Zhao, **g Cai, Jia-Cong Ye, Yi-Tai **ao… in Molecular Imaging and Biology (2020)