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Article
Open AccessIL-27-induced PD-L1highSca-1+ innate lymphoid cells suppress contact hypersensitivity in an IL-10-dependent manner
Innate lymphoid cells (ILCs) play an important role in maintaining tissue homeostasis and various inflammatory responses. ILCs are typically classified into three subsets, as is the case for T-cells. Recent st...
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Article
Open AccessEmbryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells
Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic manifestations characterized by swelling and redness. While mes...
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Article
Open AccessIntratubular crystal formation in the exposed dentin from nano-sized calcium silicate for dentin hypersensitivity treatment
The aim of this study is to evaluate intratubular crystal formation from the experimental material consisting of dicalcium silicate (C2S) and tricalcium silicate (C3S) with nano-scaled particle size. A total of t...
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Article
Open AccessRail Surface Defect Detection and Analysis Using Multi-Channel Eddy Current Method Based Algorithm for Defect Evaluation
The railroad rail support trains and contributes to their operation. Internal and surface defects occur on the rail due to various combinations of causes including fatigue loading and cyclic tension and compre...
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Article
Open AccessDeep learning for early dental caries detection in bitewing radiographs
The early detection of initial dental caries enables preventive treatment, and bitewing radiography is a good diagnostic tool for posterior initial caries. In medical imaging, the utilization of deep learning ...
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Article
Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signaling
Propionate is a short-chain fatty acid (SCFA) mainly produced from carbohydrates by gut microbiota. Sodium propionate (SP) has shown to suppress the invasion in G protein-coupled receptor 41 (GPR41) and GPR43-...
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Article
The physical properties and anticariogenic effect of experimental resin cement containing ursolic acid
The aim was to evaluate the physical properties and anti-bacterial activity of resin cement containing ursolic acid (UA) and determine the optimal concentration of UA. Five types of experimental resin cement w...
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Article
Triglyceride to high density lipoprotein cholesterol ratio and its association with periodontal disease in Korean adults: findings based on the 2012–2014 Korean national health and nutrition examination survey
The aim of this study is to evaluate whether the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio is associated with periodontal disease in Korean adults.
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Article
Effects of two fast-setting calcium-silicate cements on cell viability and angiogenic factor release in human pulp-derived cells
Mineral trioxide aggregate (MTA) is considered a pulp-cap** agent of choice, but has the drawback of a long setting time. This study aimed to assess two different types of calcium-silicate cements as pulp-ca...
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Article
Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling
A bimodal switch model is widely used to describe transcriptional regulation by the thyroid hormone receptor (TR). In this model, the unliganded TR forms stable, chromatin-bound complexes with transcriptional ...
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Reference Work Entry In depth
Concentration Gradient Generation and Control
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Chapter
Activation of PI3K by Thyroid Hormone Nuclear Receptors
Thyroid hormone receptors (TRs) mediate the diverse biological activities of thyroid hormone T3 in growth, differentiation, and development and in maintaining metabolic homeostasis. Three major T3 binding TR i...
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Living Reference Work Entry In depth
Concentration Gradient Generation and Control
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Article
High-density immobilization of antibodies onto nanobead-coated cyclic olefin copolymer plastic surfaces for application as a sensitive immunoassay chip
Our research efforts have been devoted to development of nanobead multilayer-based sensitive immunoassays on cyclic olefin copolymer (COC) plastic surfaces. To facilitate nanobead attachment and impart antibio...
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Article
Integrated Microfluidics Platforms for Investigating Injury and Regeneration of CNS Axons
We describe the development of experimental platforms to quantify the regeneration of injured central nervous system (CNS) neurons by combining engineering technologies and primary neuronal cultures. Although ...
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Article
Agrobacterium-mediated transformation using embryogenic calli in Satsuma mandarin (Citrus unshiu Marc.) cv. Miyagawa wase
Agrobacterium-mediated transformation in Satsuma mandarin (Citrus unshiu Marc.) cv. Miyagawa wase was achieved with reasonable transformation efficiency of about 22%, which was the percentage of transgenic plantl...
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Article
Functional expression of miraculin, a taste-modifying protein, in Transgenic Miyagawa Wase Satsuma mandarin (Citrus unshiu Marc.)
Miraculin is a taste modifying plant protein, which displays a peculiar property of being able to modify sour taste into sweet taste. Thus, there has been an increasing interest in miraculin due to this amazin...
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Article
Expression profiling of cultivar-related genes in Satsuma mandarins, Miyagawa wase and Ueno wase
Satsuma mandarin (Citrus unshiu Marc.) is characterized by its tender peel and seedless nature. The representative cultivar of Satsuma mandarin is Miyagawa wase. Another cultivar, Ueno wase was developed from the...
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Reference Work Entry In depth
Concentration Gradient Generation and Control
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Article
Open AccessA hybrid microfluidic-vacuum device for direct interfacing with conventional cell culture methods
Microfluidics is an enabling technology with a number of advantages over traditional tissue culture methods when precise control of cellular microenvironment is required. However, there are a number of practic...
