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Open AccessMagnesium–ibogaine therapy in veterans with traumatic brain injuries
Traumatic brain injury (TBI) is a leading cause of disability. Sequelae can include functional impairments and psychiatric syndromes such as post-traumatic stress disorder (PTSD), depression and anxiety. Speci...
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Article
Results of a Social Network Testing Intervention for HIV in Infectious Disease Clinics
Social networks can be leveraged to identify undiagnosed HIV-infected individuals. The NC-LINK clinic-based testing initiative utilized these networks to achieve a 5% (95% CI 1.1–8.9%) positivity rate by provi...
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Past Care Predicts Future Care in Out-of-Care People Living with HIV: Results of a Clinic-Based Retention-in-Care Intervention in North Carolina
Poor retention in care is associated with higher viral load (VL) results and decreased rates of viral load suppression (VS) in people living with HIV (PLWH). Therefore, improving retention in HIV care is a pri...
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Article
Open AccessCorticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression
Corticotropin-releasing factor signaling through CRF receptor type 1 (CRF1) has been shown to contribute to learning and memory function. A haplotype of alleles T-A-T in a set of common polymorphisms in the gene ...
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Erratum: Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Nat. Med.; 10.1038/nm.4246; corrected online 19 December 2016 In the version of this article initially published online, the abstract contained two typos reading, “Like to other neuropsychiatric disorders,...”...
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Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Using functional MRI in a large multisite sample of more that 1,000 patients, four distinct neurophysiological biotypes of depression are defined. These biotypes are used to develop diagnostic classifiers that...
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Article
Decreased Hypothalamic Functional Connectivity with Subgenual Cortex in Psychotic Major Depression
Hypothalamus communication with the rest of the brain and peripheral target tissues is critically important for many physiological and psychological functions. These functions include maintaining neuroendocrin...
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Article
The Structure of Psychopathology in a Community Sample of Preschoolers
Despite growing interest in the development of alternative diagnostic classification systems for psychopathology in young children, little is known about the adequacy of the DSM symptom structure for describin...
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Article
USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers
USP32, on chromosomal band 17q23.1-17q23.2, is a highly conserved but uncharacterized gene that gave rise during evolution to a well-known hominoid-specific proto-oncogene, USP6. We investigated the expression pr...
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Reply: Clinical and Biological Effects of Mifepristone Treatment for Psychotic Treatment
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Clinical and Biological Effects of Mifepristone Treatment for Psychotic Depression
Psychotic major depression (PMD) is found to be a relatively common psychiatric condition that affects up to nearly 20% of patients with major depression. Previous studies by our group have shown rapid reversa...
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Open AccessNeuropsychological effects of escitalopram treatment in middle-aged women