23 Result(s)
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Jeanie L. Y. Cheong
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Article
Open AccessBrain volume and neurodevelopment at 13 years following sepsis in very preterm infants
Associations of neonatal infection with brain growth and later neurodevelopmental outcomes in very preterm (VP) infants are unclear. This study aimed to assess associations of neonatal sepsis in VP infants wit...
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Open AccessUpdates to the Melbourne Children’s Regional Infant Brain Software Package (M-CRIB-S)
The delineation of cortical areas on magnetic resonance images (MRI) is important for understanding the complexities of the develo** human brain. The previous version of the Melbourne Children's Regional Inf...
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Childhood outcomes after maternal antenatal sildenafil treatment for severe early-onset fetal growth restriction: a randomized trial (STRIDER NZAus)
In this follow-up at 2.5 years of children from the STRIDER NZAus Trial (N = 112), in which women with singleton pregnancies affected by severe early fetal growth restriction were randomized to sildenafil citrate...
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Open AccessIntratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: statistical analysis plan for the international, multicenter, randomized PLUSS trial
Bronchopulmonary dysplasia (BPD), an inflammatory-mediated chronic lung disease, is common in extremely preterm infants born before 28 weeks’ gestation and is associated with an increased risk of adverse neuro...
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Open AccessComparative evaluation of the health utilities index mark 3 and the short form 6D: evidence from an individual participant data meta-analysis of very preterm and very low birthweight adults
The most appropriate preference-based health-related quality of life (HRQoL) instruments for trials or research studies that ascertain the consequences of individuals born very preterm and/or low birthweight (...
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Open AccessIntratracheal budesonide mixed with surfactant to increase survival free of bronchopulmonary dysplasia in extremely preterm infants: study protocol for the international, multicenter, randomized PLUSS trial
Bronchopulmonary dysplasia (BPD), an inflammatory-mediated chronic lung disease, is common in extremely preterm infants born before 28 weeks’ gestation and is associated with an increased risk of adverse neuro...
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Open AccessADHD symptoms and diagnosis in adult preterms: systematic review, IPD meta-analysis, and register-linkage study
This study examined differences in ADHD symptoms and diagnosis between preterm and term-born adults (≥18 years), and tested if ADHD is related to gestational age, birth weight, multiple births, or neonatal com...
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Open AccessA prospective, longitudinal, case–control study to evaluate the neurodevelopment of children from birth to adolescence exposed to COVID-19 in utero
The Coronavirus disease (COVID-19) pandemic has created unprecedented acute global health challenges. However, it also presents a set of unquantified and poorly understood risks in the medium to long term, spe...
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Open AccessHealth-Related Quality-of-Life Outcomes of Very Preterm or Very Low Birth Weight Adults: Evidence From an Individual Participant Data Meta-Analysis
Assessment of health-related quality of life for individuals born very preterm and/or low birthweight (VP/VLBW) offers valuable complementary information alongside biomedical assessments. However, the impact o...
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White matter tracts related to memory and emotion in very preterm children
Very preterm (VP) children are at risk of memory and emotional impairments; however, the neural correlates remain incompletely defined. This study investigated the effect of VP birth on white matter tracts tra...
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Open AccessThe use of proteomics for blood biomarker research in premature infants: a sco** review
Over the last decade, the use of proteomics in the setting of prematurity has increased and has enabled researchers to successfully identify biomarkers for an array of associated morbidities. The objective of ...
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Article
Longitudinal growth of the basal ganglia and thalamus in very preterm children
The impact of very preterm (VP) birth on the development of individual basal ganglia nuclei and the thalamus during childhood remains unclear. We first aimed to compare (1a) the volumes of individual basal gan...
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Neonatal brain abnormalities and brain volumes associated with goal setting outcomes in very preterm 13-year-olds
Executive dysfunction including impaired goal setting (i.e., planning, organization skills, strategic reasoning) is documented in children born very preterm (VP; <30 weeks/<1250 g), however the neurological ba...
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Open AccessParcellation of the neonatal cortex using Surface-based Melbourne Children’s Regional Infant Brain atlases (M-CRIB-S)
Longitudinal studies measuring changes in cortical morphology over time are best facilitated by parcellation schemes compatible across all life stages. The Melbourne Children’s Regional Infant Brain (M-CRIB) a...
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Open AccessTracking regional brain growth up to age 13 in children born term and very preterm
Serial regional brain growth from the newborn period to adolescence has not been described. Here, we measured regional brain growth in 216 very preterm (VP) and 45 full-term (FT) children. Brain MRI was perfor...
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Long Term Outcomes in Moderate and Late Preterm Infants
Moderate and late preterm births (MLP, 32–36 weeks of gestation) comprise over 80% of all preterm infants, and their birth rates are rising worldwide. MLP infants have higher rates of respiratory ill-health an...
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Basal ganglia and thalamic tract connectivity in very preterm and full-term children; associations with 7-year neurodevelopment
Altered basal ganglia and thalamic connectivity may be critical for cognitive, motor and behavioural impairments common to very preterm (<32 weeks’ gestational age) children. This study aims to (1) compare cor...
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Early environment and long-term outcomes of preterm infants
Prematurity is associated with an increased risk of long-term health and neurodevelopmental problems. Key perinatal and neonatal factors that affect these outcomes have long been studied. However, more recentl...
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Neonatal basal ganglia and thalamic volumes: very preterm birth and 7-year neurodevelopmental outcomes
This study aims to (i) compare volumes of individual basal ganglia nuclei (caudate nucleus, pallidum, and putamen) and the thalamus between very preterm (VP) and term-born infants at term-equivalent age; (ii) ...
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Open AccessAn epigenetic clock for gestational age at birth based on blood methylation data
Gestational age is often used as a proxy for developmental maturity by clinicians and researchers alike. DNA methylation has previously been shown to be associated with age and has been used to accurately esti...
