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Open AccessBrain volume and neurodevelopment at 13 years following sepsis in very preterm infants
Associations of neonatal infection with brain growth and later neurodevelopmental outcomes in very preterm (VP) infants are unclear. This study aimed to assess associations of neonatal sepsis in VP infants wit...
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Article
Open AccessUpdates to the Melbourne Children’s Regional Infant Brain Software Package (M-CRIB-S)
The delineation of cortical areas on magnetic resonance images (MRI) is important for understanding the complexities of the develo** human brain. The previous version of the Melbourne Children's Regional Inf...
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Article
Open AccessLow to moderate prenatal alcohol exposure and neurodevelopment in a prospective cohort of early school aged children
Evidence is strong for adverse fetal effects of high level or chronic prenatal alcohol exposure (PAE), but many pregnant women continue to drink at lower levels. The ‘Asking Questions about Alcohol in pregnanc...
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Open AccessA data driven approach to identify trajectories of prenatal alcohol consumption in an Australian population-based cohort of pregnant women
Accurate information on dose, frequency and timing of maternal alcohol consumption is critically important when investigating fetal risks from prenatal alcohol exposure. Identification of distinct alcohol use ...
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Article
White matter tracts related to memory and emotion in very preterm children
Very preterm (VP) children are at risk of memory and emotional impairments; however, the neural correlates remain incompletely defined. This study investigated the effect of VP birth on white matter tracts tra...
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Article
Longitudinal growth of the basal ganglia and thalamus in very preterm children
The impact of very preterm (VP) birth on the development of individual basal ganglia nuclei and the thalamus during childhood remains unclear. We first aimed to compare (1a) the volumes of individual basal gan...
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Article
Neonatal brain abnormalities and brain volumes associated with goal setting outcomes in very preterm 13-year-olds
Executive dysfunction including impaired goal setting (i.e., planning, organization skills, strategic reasoning) is documented in children born very preterm (VP; <30 weeks/<1250 g), however the neurological ba...
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Open AccessParcellation of the neonatal cortex using Surface-based Melbourne Children’s Regional Infant Brain atlases (M-CRIB-S)
Longitudinal studies measuring changes in cortical morphology over time are best facilitated by parcellation schemes compatible across all life stages. The Melbourne Children’s Regional Infant Brain (M-CRIB) a...
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Open AccessTracking regional brain growth up to age 13 in children born term and very preterm
Serial regional brain growth from the newborn period to adolescence has not been described. Here, we measured regional brain growth in 216 very preterm (VP) and 45 full-term (FT) children. Brain MRI was perfor...
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Basal ganglia and thalamic tract connectivity in very preterm and full-term children; associations with 7-year neurodevelopment
Altered basal ganglia and thalamic connectivity may be critical for cognitive, motor and behavioural impairments common to very preterm (<32 weeks’ gestational age) children. This study aims to (1) compare cor...
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Article
Open AccessWorking Memory Training Is Associated with Changes in Resting State Functional Connectivity in Children Who Were Born Extremely Preterm: a Randomized Controlled Trial
Children born extremely preterm (EP; < 28 weeks of gestation) or extremely low birth weight (ELBW; < 1000 g) are at increased risk of working memory deficits compared with their term-born peers and may benefit...
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Article
Open AccessHistologic chorioamnionitis in preterm infants: correlation with brain magnetic resonance imaging at term equivalent age
To explore the associations between histologic chorioamnionitis with brain injury, maturation and size on magnetic resonance imaging (MRI) of preterm infants at term equivalent age.
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Article
Neonatal basal ganglia and thalamic volumes: very preterm birth and 7-year neurodevelopmental outcomes
This study aims to (i) compare volumes of individual basal ganglia nuclei (caudate nucleus, pallidum, and putamen) and the thalamus between very preterm (VP) and term-born infants at term-equivalent age; (ii) ...
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Article
Altered posterior cingulate brain metabolites and cognitive dysfunction in preterm adolescents
Extremely preterm (EP, <28 wk gestation) individuals have increased the risk of cognitive deficits compared with controls. The posterior cingulate region has an important role in cognitive function, but how th...
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Article
Moderate and late preterm infants exhibit widespread brain white matter microstructure alterations at term-equivalent age relative to term-born controls
Despite the many studies documenting cerebral white matter microstructural alterations associated with very preterm birth (<32 weeks’ gestation), there is a dearth of similar research in moderate and late pret...
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Article
A New MRI-Based Pediatric Subcortical Segmentation Technique (PSST)
Volumetric and morphometric neuroimaging studies of the basal ganglia and thalamus in pediatric populations have utilized existing automated segmentation tools including FIRST (Functional Magnetic Resonance Im...
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Article
Diffusion tractography and neuromotor outcome in very preterm children with white matter abnormalities
Moderate-to-severe white matter abnormality (WMA) in the newborn has been shown to produce persistent disruptions in cerebral connectivity but does not universally result in neurodevelopmental disability in ve...
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Article
Open AccessNeurobehaviour between birth and 40 weeks’ gestation in infants born <30 weeks’ gestation and parental psychological wellbeing: predictors of brain development and child outcomes
Infants born <30 weeks’ gestation are at increased risk of long term neurodevelopmental problems compared with term born peers. The predictive value of neurobehavioural examinations at term equivalent age in v...
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Open AccessPreventing academic difficulties in preterm children: a randomised controlled trial of an adaptive working memory training intervention – IMPRINT study
Very preterm children exhibit difficulties in working memory, a key cognitive ability vital to learning information and the development of academic skills. Previous research suggests that an adaptive working m...
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Optimizing Hippocampal Segmentation in Infants Utilizing MRI Post-Acquisition Processing
This study aims to determine the most reliable method for infant hippocampal segmentation by comparing magnetic resonance (MR) imaging post-acquisition processing techniques: contrast to noise ratio (CNR) enha...
