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Article
Open AccessResilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)
Critical-illness survivors may experience post-traumatic stress disorder (PTSD) and quality-of-life impairments. Resilience may protect against psychological trauma but has not been adequately studied after cr...
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Article
Seeking the road to healing after intensive care unit: we need a personalised global positioning system
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A randomized clinical trial to evaluate the effect of post-intensive care multidisciplinary consultations on mortality and the quality of life at 1 year
Critical illness is associated with long-term increased mortality and impaired quality of life (QoL). We assessed whether multidisciplinary consultations would improve outcome at 12 months (M12) after intensiv...
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Article
Open AccessClinical description and outcome of overall varicella-zoster virus-related organ dysfunctions admitted in intensive care units: the VAZOREA cohort study
Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in IC...
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Article
Open AccessImpact of COVID-19 on posttraumatic stress disorder in ICU survivors: a prospective observational comparative cohort study
Posttraumatic stress disorder (PTSD) after a stay in the intensive care unit (ICU) can affect one in five ICU survivors. At the beginning of the coronavirus disease 2019 (COVID-19) pandemic, admission to the I...
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Article
Renal replacement therapy initiation strategies in comatose patients with severe acute kidney injury: a secondary analysis of a multicenter randomized controlled trial
The effect of renal replacement therapy (RRT) in comatose patients with acute kidney injury (AKI) remains unclear. We compared two RRT initiation strategies on the probability of awakening in comatose patients...
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Open AccessCorrection: Clinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study
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Article
Open AccessFluid balance control in critically ill patients: results from as-treated analyses of POINCARE-2 randomized trial
Intention-to-treat analyses of POINCARE-2 trial led to inconclusive results regarding the effect of a conservative fluid balance strategy on mortality in critically ill patients. The present as-treated analysi...
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Article
Open AccessCorrection: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study
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Article
Open AccessRole of the interstitium during septic shock: a key to the understanding of fluid dynamics?
While not traditionally included in the conceptual understanding of circulation, the interstitium plays a critical role in maintaining fluid homeostasis. Fluid balance regulation is a critical aspect of septic...
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Article
Open AccessInfluence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study
Survivors after acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) are at high risk of develo** respiratory sequelae and functional impairment. The healthcare crisis caused...
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Article
Open AccessClinical spectrum and prognostic impact of cancer in critically ill patients with HIV: a multicentre cohort study
Both AIDS-defining and non-AIDS-defining cancers (ADC/NADC) predispose people living with HIV (PLHIV) to critical illnesses. The objective of this multicentre study was to investigate the prognostic impact of ...
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Article
Open AccessDifferential effect on mortality of the timing of initiation of renal replacement therapy according to the criteria used to diagnose acute kidney injury: an IDEAL-ICU substudy
This substudy of the randomized IDEAL-ICU trial assessed whether the timing of renal replacement therapy (RRT) initiation has a differential effect on 90-day mortality, according to the criteria used to diagno...
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Article
Correction: Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit
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Open AccessLimitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study
Limitations of life-sustaining therapies (LST) practices are frequent and vary among intensive care units (ICUs). However, scarce data were available during the COVID-19 pandemic when ICUs were under intense p...
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Article
Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit
Although eosinophil-induced manifestations can be life-threatening, studies focusing on the epidemiology and clinical manifestations of eosinophilia in the intensive care unit (ICU) are lacking.
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Article
Open AccessFluid balance control in critically ill patients: results from POINCARE-2 stepped wedge cluster-randomized trial
In critically ill patients, positive fluid balance is associated with excessive mortality. The POINCARE-2 trial aimed to assess the effectiveness of a fluid balance control strategy on mortality in critically ...
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Article
Open AccessEndotracheal tube biofilm in critically ill patients during the COVID-19 pandemic : description of an underestimated microbiological compartment
Biofilm (BF) growth is believed to play a major role in the development of ventilator-associated pneumonia (VAP) in the intensive care unit. Despite concerted efforts to understand the potential implication of...
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Article
Remote ischemic conditioning in septic shock: the RECO-Sepsis randomized clinical trial
To determine whether remote ischemic conditioning (RECO), compared to standard care, limits the severity and the consequences of multiple organ failure in patients with septic shock.
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Article
Open AccessOutcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data
Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis of the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. ...
