141 Result(s)

Article

Prognosticating the outcome of intensive care in older patients—a narrative review

Prognosis determines major decisions regarding treatment for critically ill patients. Statistical models have been developed to predict the probability of survival and other outcomes of intensive care. Althoug...

Michael Beil, Rui Moreno, Jakub Fronczek, Yuri Kogan… in Annals of Intensive Care (2024)

Article

Prognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter study

Prognostication of outcome in severe stroke patients necessitating invasive mechanical ventilation poses significant challenges. The objective of this study was to assess the prognostic significance and preval...

Sarah Benghanem, Nathalie Kubis, Etienne Gayat, Ambre Loiodice… in Critical Care (2024)

Article

Critical care beyond organ support: the importance of geriatric rehabilitation

Very old critically ill patients pose a growing challenge for intensive care. Critical illness and the burden of treatment in the intensive care unit (ICU) can lead to a long-lasting decline of functional and ...

Jeremy M. Jacobs, Ana Rahamim, Michael Beil, Bertrand Guidet… in Annals of Intensive Care (2024)

Article

The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years

Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on...

Dylan W. de Lange, Ivo W. Soliman, Susannah Leaver… in Annals of Intensive Care (2024)

Article

Prediction of esophagogastroduodenoscopy therapeutic usefulness for in-ICU suspected upper gastrointestinal bleeding: the SUGIBI score study

Suspected upper gastrointestinal bleeding (SUGIB) is a common issue during ICU stay. In the absence of specific guidelines on the indication and timing of esophagogastroduodenoscopy (EGD), there is substantial...

Victor Penaud, Thibault Vieille, Tomas Urbina, Vincent Bonny… in Annals of Intensive Care (2024)

Article

Albumin versus saline infusion for sepsis-related peripheral tissue hypoperfusion: a proof-of-concept prospective study

Albumin has potential endothelial protective effects through antioxidant and anti-inflammatory properties. However, the effect of albumin on peripheral tissue perfusion in human sepsis remains poorly known.

Paul Gabarre, Cyrielle Desnos, Alexandra Morin, Louai Missri, Tomas Urbina… in Critical Care (2024)

Article

Frailty’s influence on 30-day mortality in old critically ill ICU patients: a bayesian analysis evaluating the clinical frailty scale

Frailty is widely acknowledged as influencing health outcomes among critically ill old patients. Yet, the traditional understanding of its impact has predominantly been through frequentist statistics. We endea...

Bernhard Wernly, Raphael Romano Bruno, Michael Beil… in Annals of Intensive Care (2023)

Article

Limiting life-sustaining treatment for very old ICU patients: cultural challenges and diverse practices

Decisions about life-sustaining therapy (LST) in the intensive care unit (ICU) depend on predictions of survival as well as the expected functional capacity and self-perceived quality of life after discharge, ...

Michael Beil, Peter Vernon van Heerden, Gavin M. Joynt… in Annals of Intensive Care (2023)

Article

Validity of the total SOFA score in patients ≥ 80 years old acutely admitted to intensive care units: a post-hoc analysis of the VIP2 prospective, international cohort study

Little is known about the performance of the Sequential Organ Failure Assessment (SOFA) score in older critically ill adults. We aimed to evaluate the prognostic impact of physiological disturbances in the six...

Kamil Polok, Jakub Fronczek, Zbigniew Putowski, Marcelina Czok… in Annals of Intensive Care (2023)

Article

Diabetes mellitus is associated with 90-day mortality in old critically ill COVID-19 patients: a multicenter prospective observational cohort study

Several studies have found an association between diabetes mellitus, disease severity and outcome in COVID-19 patients. Old critically ill patients are particularly at risk. This study aimed to investigate the...

Timo Mayerhöfer, Sebastian Klein, Bernhard Wernly, Hans Flaatten… in Infection (2023)

Article

Sonometric assessment of cough predicts extubation failure: SonoWean—a proof-of-concept study

Extubation failure is associated with increased mortality. Cough ineffectiveness may be associated with extubation failure, but its quantification for patients undergoing weaning from invasive mechanical venti...

Vincent Bonny, Jeremie Joffre, Paul Gabarre, Tomas Urbina, Louai Missri… in Critical Care (2023)

Article

Outcomes of patients aged ≥80 years with respiratory failure initially treated with non-invasive ventilation in European intensive care units before and during COVID-19 pandemic

Non-invasive ventilation (NIV) has been commonly used to treat acute respiratory failure due to COVID-19. In this study we aimed to compare outcomes of older critically ill patients treated with NIV before and...

Kamil Polok, Jakub Fronczek, Bertrand Guidet, Antonio Artigas… in Annals of Intensive Care (2023)

Article

The impact of age-related syndromes on ICU process and outcomes in very old patients

In this narrative review, we describe the most important age-related “syndromes” found in the old ICU patients. The syndromes are frailty, comorbidity, cognitive decline, malnutrition, sarcopenia, loss of func...

Hélène Vallet, Bertrand Guidet, Ariane Boumendil… in Annals of Intensive Care (2023)

Article

Improving frailty assessment: the task is not finished

Bernhard Wernly, Hans Flaatten, Susannah Leaver, Bertrand Guidet… in Critical Care (2023)

Article

The role of clinical phenotypes in decisions to limit life-sustaining treatment for very old patients in the ICU

Limiting life-sustaining treatment (LST) in the intensive care unit (ICU) by withholding or withdrawing interventional therapies is considered appropriate if there is no expectation of beneficial outcome. Prog...

Oded Mousai, Lola Tafoureau, Tamar Yovell, Hans Flaatten… in Annals of Intensive Care (2023)

Article

The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data

This large-scale analysis pools individual data about the Clinical Frailty Scale (CFS) to predict outcome in the intensive care unit (ICU).

Raphael Romano Bruno, Bernhard Wernly, Sean M. Bagshaw… in Annals of Intensive Care (2023)

Article

Reversible skin microvascular hyporeactivity in patients with immune-mediated thrombocytopenic thrombotic purpura

Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare disease characterized by arteriolar and capillary microthrombosis precipitating organ failure. However, the contribution of endothelial dysf...

Jérémie Joffre, Lisa Raia, Tomas Urbina, Vincent Bonny, Paul Gabarre… in Critical Care (2023)

Article

ICU health care workers opinion on physician-assisted-suicide and euthanasia: a French survey

In France, physician-assisted suicide or euthanasia are not legal but are still debated. French intensive care unit (ICU) health care workers (HCWs) have an insider’s perspective on the global quality of the p...

Mathieu Acquier, Alexandre Boyer, Bertrand Guidet… in Annals of Intensive Care (2023)

Article

Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study

Limitations of life-sustaining therapies (LST) practices are frequent and vary among intensive care units (ICUs). However, scarce data were available during the COVID-19 pandemic when ICUs were under intense p...

Mikhael Giabicani, Christophe Le Terrier, Antoine Poncet, Bertrand Guidet… in Critical Care (2023)