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Article
Open AccessA proteome scale study reveals how plastic surfaces and agitation promote protein aggregation
Protein aggregation in biotherapeutics can reduce their activity and effectiveness. It may also promote immune reactions responsible for severe adverse effects. The impact of plastic materials on protein desta...
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Article
Open AccessTime-resolved cathodoluminescence of DNA triggered by picosecond electron bunches
Despite the tremendous importance of so-called ionizing radiations (X-rays, accelerated electrons and ions) in cancer treatment, most studies on their effects have focused on the ionization process itself, and...
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Article
Interaction of TiO2 nanoparticles with proteins from aquatic organisms: the case of gill mucus from blue mussel
To better understand the mechanisms of TiO2 nanoparticle (NP) uptake and toxicity in aquatic organisms, we investigated the interaction of NPs with the proteins found in gill mucus from blue mussels. Mucus is sec...
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Article
The nano-bio interface mapped by oxidative footprinting of the adsorption sites of myoglobin
Oxidative footprinting has been used to study the structure of macromolecular assemblies such as protein-protein and protein-ligand complexes. We propose a novel development of this technique to probe the prot...