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Article
Open AccessType 1 interferons and Foxo1 down-regulation play a key role in age-related T-cell exhaustion in mice
Foxo family transcription factors are critically involved in multiple processes, such as metabolism, quiescence, cell survival and cell differentiation. Although continuous, high activity of Foxo transcription...
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Article
Open AccessIntrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation
Invariant natural killer T (NKT) cell subsets are defined based on their cytokine-production profiles and transcription factors. Their distribution is different in C57BL/6 (B6) and BALB/c mice, with a bias for...
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Article
Clinical phenotype and cytokine profile of adult IgA vasculitis with joint involvement
Joint involvement can be observed during the course of adult IgA vasculitis (IgAV). However, clinical picture, prognosis, or pathophysiological data associated with this condition have been overlooked. We aime...
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Article
Open AccessHighly scalable multicycle THz production with a homemade periodically poled macrocrystal
The THz regime is widely appealing across many disciplines including solid-state physics, life sciences, and increasingly in particle acceleration. Multicycle THz pulses are typically formed via optical rectif...
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Article
Open AccessTime-resolved cathodoluminescence of DNA triggered by picosecond electron bunches
Despite the tremendous importance of so-called ionizing radiations (X-rays, accelerated electrons and ions) in cancer treatment, most studies on their effects have focused on the ionization process itself, and...
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Article
Inverted Polymer Solar Cells with a Reduced Graphene Oxide/Poly (3,4-Ethylene Dioxythiophene):Poly(4-Styrene Sulfonate) (PEDOT:PSS) Hole Transport Layer
In this study, high-efficiency inverted polymer solar cells were developed by using graphene oxide/poly(3,4-ethylene-dioxythiophene):poly(4-styrene-sulfonate) (GO/PEDOT:PSS) composites films acting as hole tra...
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Article
Frequency electrical conductivity dependence and dielectric relaxation of ZnO–P2O5/Co composites
This work focuses on the experimental study of the conductivity and the permittivity of ZnO–P2O5/Co (ZP/Co) composites as function of frequency in the range of 100–106 Hz at room temperature. The conductivity evo...
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Article
Open AccessProfiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
Despite being implicated in non-lymphoid tissues, non-recirculating T cells may also exist in secondary lymphoid organs (SLO). However, a detailed characterization of this lymphoid-resident T cell pool has not...
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Article
Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells
Upon activation, naive CD4 T cells differentiate into a variety of T-helper-cell subsets characterized by different cytokine production and functions. Currently, lineage commitment is considered to depend most...