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  1. Article

    Open Access

    Type 1 interferons and Foxo1 down-regulation play a key role in age-related T-cell exhaustion in mice

    Foxo family transcription factors are critically involved in multiple processes, such as metabolism, quiescence, cell survival and cell differentiation. Although continuous, high activity of Foxo transcription...

    Aurélie Durand, Nelly Bonilla, Théo Level, Zoé Ginestet in Nature Communications (2024)

  2. Article

    Open Access

    Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation

    Invariant natural killer T (NKT) cell subsets are defined based on their cytokine-production profiles and transcription factors. Their distribution is different in C57BL/6 (B6) and BALB/c mice, with a bias for...

    Ludivine Amable, Luis Antonio Ferreira Martins, Remi Pierre in Nature Communications (2023)

  3. No Access

    Article

    Clinical phenotype and cytokine profile of adult IgA vasculitis with joint involvement

    Joint involvement can be observed during the course of adult IgA vasculitis (IgAV). However, clinical picture, prognosis, or pathophysiological data associated with this condition have been overlooked. We aime...

    Alice Delapierre, Benjamin Terrier, Evangéline Pillebout in Clinical Rheumatology (2022)

  4. Article

    Open Access

    Highly scalable multicycle THz production with a homemade periodically poled macrocrystal

    The THz regime is widely appealing across many disciplines including solid-state physics, life sciences, and increasingly in particle acceleration. Multicycle THz pulses are typically formed via optical rectif...

    François Lemery, Thomas Vinatier, Frank Mayet, Ralph Aßmann in Communications Physics (2020)

  5. Article

    Open Access

    Time-resolved cathodoluminescence of DNA triggered by picosecond electron bunches

    Despite the tremendous importance of so-called ionizing radiations (X-rays, accelerated electrons and ions) in cancer treatment, most studies on their effects have focused on the ionization process itself, and...

    Jean Philippe Renault, Bruno Lucas, Thomas Gustavsson, Alain Huetz in Scientific Reports (2020)

  6. No Access

    Article

    Inverted Polymer Solar Cells with a Reduced Graphene Oxide/Poly (3,4-Ethylene Dioxythiophene):Poly(4-Styrene Sulfonate) (PEDOT:PSS) Hole Transport Layer

    In this study, high-efficiency inverted polymer solar cells were developed by using graphene oxide/poly(3,4-ethylene-dioxythiophene):poly(4-styrene-sulfonate) (GO/PEDOT:PSS) composites films acting as hole tra...

    Meryem Goumri, Bruno Lucas, Bernard Ratier in Journal of Electronic Materials (2019)

  7. No Access

    Article

    Frequency electrical conductivity dependence and dielectric relaxation of ZnO–P2O5/Co composites

    This work focuses on the experimental study of the conductivity and the permittivity of ZnO–P2O5/Co (ZP/Co) composites as function of frequency in the range of 100–106 Hz at room temperature. The conductivity evo...

    Omar Oabi, Abdelkrim Maaroufi, Bruno Lucas in Journal of Materials Science: Materials in… (2018)

  8. Article

    Open Access

    Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota

    Despite being implicated in non-lymphoid tissues, non-recirculating T cells may also exist in secondary lymphoid organs (SLO). However, a detailed characterization of this lymphoid-resident T cell pool has not...

    Aurélie Durand, Alexandra Audemard-Verger, Vincent Guichard in Nature Communications (2018)

  9. No Access

    Article

    Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells

    Upon activation, naive CD4 T cells differentiate into a variety of T-helper-cell subsets characterized by different cytokine production and functions. Currently, lineage commitment is considered to depend most...

    Bruno Martin, Cédric Auffray, Arnaud Delpoux, Arnaud Pommier in Nature Communications (2013)