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Open AccessPharmacological treatment of cancer pain and opioid induced nausea and vomiting: online survey and comparison with current guidelines
We assumed that in Palliative Care, even in common clinical situations, the choice of drugs differs substantially between physicians. Therefore, we assessed the practice of pharmaceutical treatment choices of ...
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Open AccessInterventions that may increase control at the end of life in persons with dementia: the cross-cultural CONT-END acceptability study protocol and pilot-testing
Interventions such as advance care planning (ACP), technology, or access to euthanasia may increase the sense of control over the end of life. In people with advanced dementia, the loss of cognitive and physic...
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Open AccessTranscutaneous electrical nerve stimulation for advanced cancer pain inpatients in specialist palliative care—a blinded, randomized, sham-controlled pilot cross-over trial
Transcutaneous electrical nerve stimulation (TENS) is a treatment option for cancer pain, but the evidence is inconclusive. We aimed to evaluate the efficacy and safety of TENS.
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Open AccessSevere symptoms and very low quality-of-life among outpatients newly diagnosed with advanced cancer: data from a multicenter cohort study
The aim of this study was to identify symptoms of severe intensity or very low scores for quality of life (QoL) domains in newly diagnosed outpatients with advanced cancer.
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Open AccessOf apples and oranges: Lessons learned from the preparation of research protocols for systematic reviews exploring the effectiveness of Specialist Palliative Care
Agreed terminology used in systematic reviews of the effectiveness of specialist palliative care ((S)PC)) is required to ensure consistency and usability and to help guide future similar reviews and the design...
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Inconsistent conclusions on QoL outcomes from the same clinical trial
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Open AccessSpecialist palliative care services for adults with advanced, incurable illness in hospital, hospice, or community settings—protocol for a systematic review
Specialist palliative care (SPC) interventions aim to relieve and prevent suffering in the physical, psychological, social, and spiritual domain. Therefore, SPC is carried out by a multi-professional team with...
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Author’s Reply to Kotlinska-Lemieszek: “Should Midazolam Drug–Drug Interactions Be of Concern to Palliative Care Physicians?”
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Cancer Pain Management: What’s New?
Decades after the publication of the World Health Organization’s analgesic ladder, cancer pain is still a major cause of suffering for patients with cancer and affects millions of people worldwide. Owing to th...
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Practicability, safety, and efficacy of a “German model” for opioid conversion to oral levo-methadone
An algorithm to convert from any other opioid to oral levo-methadone was developed in Germany, the German model of levo-methadone conversion (GMLC). According to this GMLC, the pre-existing opioid is stopped, ...
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Drug Interactions in Dying Patients
Background: Patients at the end of life often receive numerous medications for symptom management. In contrast to all other clinical situations, the aim of pharmacotherapy is strictly focused on quality of life.
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Recommending early integration of palliative care — does it work?
In 2006, our comprehensive cancer center decided to implement early integration (EI) of palliative care (PC) by (a) literally adopting the WHO definition of PC into cancer care guidelines and (b) providing a PC c...
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Evaluation of diagnostic and treatment approaches towards acute dyspnea in a palliative care setting among medical students at the University of Vienna
GRUNDLAGEN: Bei Patienten mit fortgeschrittener Krebserkrankung ist Dyspnoe eines der häufigsten Symptome. Opioide zählen mit zur Standardtherapie. ZIEL: Ziel der Studie war, den Wissenstand von Studenten im 8...
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Standardizing integration of palliative care into comprehensive cancer therapy—a disease specific approach
Our comprehensive cancer centre adopted the WHO recommendation literally in the cancer care guidelines to implement the early integration (EI) of palliative care (PC). Evaluation of the first 2 years of this a...
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Open AccessDifferential palliative care issues in patients with primary and secondary brain tumours
Cancer may affect the central nervous system either by primary or secondary brain tumours (PBT/SBT). Specific needs of these patients and special requirements of services caring for them have not been adequate...
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Pathophysiology and diagnosis of dyspnea in patients with advanced cancer
Die Prävalenz von Dyspnoe bei Tumorpatienten im fortgeschrittenen Stadium bewegt sich von 19 % bis 64 %. Um Dyspnoe bei Tumorpatienten adäquat zu behandeln, ist es notwendig, die genauen Mechanismen der Dyspno...