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Article
Glucocorticoid Receptor Down-Regulation Affects Neural Stem Cell Proliferation and Hippocampal Neurogenesis
Dysregulation of the hypothalamic–pituitary–adrenal axis and abnormalities in the glucocorticoid receptor (GR) have been linked to major depressive disorder. Given the critical role of GR in stress response re...
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Article
Open AccessAssociation of parental depression with adolescent children’s psychological well-being and health behaviors
Parental depression is a significant problem that negatively affects parents’ welfare and influences family dynamics, children’s academic and health behaviors, and mental health. However, there is limited evid...
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Article
Renewable Energy Sources: From Non-Dispatchable to Dispatchable, and Their Application for Power System Carbon Neutrality Considering System Reliability
The trend of integrating renewable energy sources (RES) into power systems to mitigate the impacts of global warming is significantly increasing. However, the variability and intermittency of these energy sour...
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Article
Open AccessPCSK9 stimulates Syk, PKCδ, and NF-κB, leading to atherosclerosis progression independently of LDL receptor
Proprotein convertase subtilisin/kexin type-9 (PCSK9) binds to and degrades low-density lipoprotein (LDL) receptor, leading to increase of LDL cholesterol in blood. Its blockers have emerged as promising thera...
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Article
Industrial Solid Waste-Based Layered Double Hydroxide Composite with Enhanced Adsorption Affinity to Congo Red, Acid Red, and Reactive Red
The synthesis of hierarchically porous materials from industrial solid waste as catalysts or adsorbents has attracted much attention in environmental pollution control. The present work highlights the synthesi...
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Article
Amelioration of Astrocyte-Mediated Neuroinflammation by EI-16004 Confers Neuroprotection in an MPTP-induced Parkinson’s Disease Model
Parkinson’s disease (PD) is a neurodegenerative disorder that results in motor impairment due to dopaminergic neuronal loss. The pathology of PD is closely associated with neuroinflammation, which can be chara...
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Article
Open AccessMachine learning-based high-frequency neuronal spike reconstruction from low-frequency and low-sampling-rate recordings
Recording neuronal activity using multiple electrodes has been widely used to understand the functional mechanisms of the brain. Increasing the number of electrodes allows us to decode more variety of function...
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Article
Comparison of Stabilization Effects of Variable Pum** Storage Hydro (VPSH) and BESS on Renewable Generation Oriented Power System
By increasing the proportion of renewable energy sources, the power system is prone to instability due to decreased system inertia and increased disturbances. For the system to remain stable, energy storage sy...
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Article
Open AccessLipid remodeling of adipose tissue in metabolic health and disease
Adipose tissue is a dynamic and metabolically active organ that plays a crucial role in energy homeostasis and endocrine function. Recent advancements in lipidomics techniques have enabled the study of the com...
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Article
Open AccessGraphene quantum dot nanocomposites: electroanalytical and optical sensor technology perspective
Electroanalytical and optical techniques are widely used in the development of nanomaterials-based sensor platforms. These techniques have a quick response, high sensitivity, and selectivity. Electroanalytical...
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Article
Open AccessSOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction
Lysophosphatidic acid receptor 4 (LPAR4) exhibits transient expression at the cardiac progenitor stage during pluripotent stem cell (PSC)-derived cardiac differentiation. Using RNA sequencing, promoter analyse...
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Article
Open AccessPeli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation
The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induce...
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Article
Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice
Adult neurogenesis generates new functional neurons from adult neural stem cells in various regions, including the subventricular zone (SVZ) of the lateral ventricles and subgranular zone (SGZ) of hippocampal ...
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Article
Open AccessSMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice
The vitamin-C-synthesizing enzyme senescent marker protein 30 (SMP30) is a cold resistance gene in Drosophila, and vitamin C concentration increases in brown adipose tissue post-cold exposure. However, the roles ...
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Article
Open AccessThree-dimensional nanoframes with dual rims as nanoprobes for biosensing
Three-dimensional (3D) nanoframe structures are very appealing because their inner voids and ridges interact efficiently with light and analytes, allowing for effective optical-based sensing. However, the real...
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Article
Open AccessNesting of multiple polyhedral plasmonic nanoframes into a single entity
The development of plasmonic nanostructures with intricate nanoframe morphologies has attracted considerable interest for improving catalytic and optical properties. However, arranging multiple nanoframes in o...
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Article
Open AccessAdipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism
Dysregulation of adipose tissue plasmalogen metabolism is associated with obesity-related metabolic diseases. We report that feeding mice a high-fat diet reduces adipose tissue lysoplasmalogen levels and incre...
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Article
Open AccessActivation of nitrogen species mixed with Ar and H2S plasma for directly N-doped TMD films synthesis
Among the transition metal dichalcogenides (TMD), tungsten disulfide (WS2) and molybdenum disulfide (MoS2) are promising sulfides for replacing noble metals in the hydrogen evolution reaction (HER) owing to their...
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Article
Open AccessPharmacokinetics and toxicity evaluation following oral exposure to bisphenol F
Bisphenol F is a substitute material for bisphenol A and is widely used in household products as a raw material for polycarbonate resin, epoxy resin, and plastic reinforcement. It is known to be mainly used in...
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Article
Functionalized polymer dielectrics for low-operating voltage organic field-effect transistors
The design of appropriate dielectrics plays a crucial role in the performance of organic field-effect transistors (FETs). Along with the active semiconductor layer, the dielectric–semiconductor interface gover...
