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Article
Rat Chromosome 1: Regional localization of seven genes (Slc9a3, Srd5a1, Esr, Tcp1, Grik5, Tnnt3, Jak2) and anchoring of the genetic linkage map to the cytogenetic map
Seven genes were regionally localized on rat Chromosome (Chr) 1, from 1p11 to 1q42, and two of these genes were also included in a linkage map. This map** work integrates the genetic linkage map and the cyto...
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Article
FISH map** of three ammonia metabolism genes (Glul, Cps1, Glud1) in rat, and the chromosomal localization of GLUL in human and Cps1 in mouse
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Map** of the ribonucleotide reductase genes (Rrm1, Rrm2) in the rat
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Article
Chromosomal assignment of three rat and human H-rev genes, putative tumor suppressors, down-regulated in malignantly HRAS-transformed cells
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Chromosomal map** of the rat Slc4a family of anion exchanger genes, Ael, Ae2, and Ae3
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Article
Regional localization of the rat genes encoding the cAMP-specific phosphodiesterases 3 (Pde4d) and 4 (Pde4b) and the tyrosinase-related protein 1 (Tyrp1)
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Article
A genetic linkage map of the rat derived from recombinant inbred strains
We have constructed a genetic linkage map in the rat by analyzing the strain distribution patterns of 500 genetic markers in a large set of recombinant inbred strains derived from the spontaneously hypertensiv...
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Article
Map** of the calcium-sensing receptor gene (CASR) to human Chromosome 3q13.3-21 by fluorescence in situ hybridization, and localization to rat Chromosome 11 and mouse Chromosome 16
The calcium-sensing receptor (CASR), a member of the G-protein coupled receptor family, is expressed in both parathyroid and kidney, and aids these organs in sensing extracellular calcium levels. Inactivating ...
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Article
Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains
Genetic monitoring is an essential component of colony management and for the rat has been accomplished primarily by using immunological and biochemical markers. Here, we report that simple sequence length pol...
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Article
A genetic map of microsatellite markers on rat Chromosome 7
Nine microsatellite loci were mapped to rat Chromosome (Chr) 7 by genetic linkage and somatic cell hybrid analysis. These loci include the gene encoding a member of the IID sub-family of cytochrome P450 (Cyp2d), ...
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Article
Map** of the gene for rat protein phosphatase 1α (Ppp1ca) to Chromosome 1
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Article
Chromosomal assignment of 11 loci in the rat by mouse-rat somatic hybrids and linkage
Eleven rat genes have been assigned to rat chromosomes by use of mouse × rat somatic hybrids and/or use of linkage to known chromosome markers. Among them, the genes for the inducible nitric oxide synthase (Nos2)...
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Article
Assignment of rat Jun family genes to Chromosome 19 (Junb), Chromosome 5q31–33 (Jun), and Chromosome 16 (Jund)
By means of somatic cell hybrids segregating rat chromosomes, we determined the chromosome localization of three rat genes of the Jun family: Jumb (Chr 19), Jun (=c-Jun) (Chr 5) and Jund (Chr 16). The Jun gene wa...
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Article
Chromosomal assignment of four genes encoding Na/H exchanger isoforms in human and rat
The plasma membrane Na/H exchanger plays an essential role in regulating intracellular pH and Na+ concentration and has been implicated in several pathophysiological conditions, including essential hypertension a...
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Somatic Cell Genetic Analysis of Growth Control
These last years, a growing number of altered genes have been implicated in neoplastic development. These genes, in their normal guise, are supposed to be involved in the control of cell growth. Two seemingly ...