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    Article

    Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis

    Investigating genetic interactions (epistasis) has proven difficult despite the recent advances of both laboratory methods and statistical developments. With no ‘best’ statistical approach available, combining...

    F B S Briggs, P P Ramsay, E Madden, J M Norris, V M Holers, T R Mikuls… in Genes & Immunity (2010)