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  1. No Access

    Article

    Mineralization and Alkaline Phosphatase Activity in Collagen Lattices Populated by Human Osteoblasts

    Adult human osteoblastic cells were grown in a native type I collagen gel. Proliferation and viability analyses showed that cells rapidly stopped dividing and became blocked in the G0G1 phase (91% on day 13)....

    A. Rattner, O. Sabido, J. Le, L. Vico, C. Massoubre… in Calcified Tissue International (2000)

  2. No Access

    Article

    Urine glycyl-L-proline increase and skin trophicity

    Glycyl-L-proline (gly-pro) is an end product of collagen metabolism that is further cleaved by prolidase (EC 3.4.13.9); the resulting proline molecules are recycled into collagen or other proteins. We postulat...

    J. Le, C. Perier, S. Peyroche, F. Rascle, M. A. Blanchon, R. Gonthier… in Amino Acids (1999)

  3. No Access

    Article

    A comparison of15N proline and13C leucine for monitoring protein biosynthesis in the skin

    The tracers L15N-proline and L(1-13C)-leucine were used to explore the synthesis of skin proteins in vivo in rabbits. They orally received a single dose containing an equimolecular mixture of L(1-13C)-leucine and...

    J. Doumit, J. Le, Prof. J. Frey, A. Chamson, C. Perier in Amino Acids (1999)

  4. No Access

    Article

    Does microbial biomass affect pelagic ecosystem efficiency? An experimental study

    Bacteria and other microorganisms in the pelagic zone participate in the recycling of organic matter and nutrients within the water column. The microbial loop is thought to enhance ecosystem efficiency through...

    J.D. Wehr, J. Le, L. Campbell in Microbial Ecology (1994)