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Article
Production of matrix metalloproteinase 2 in fibroblast reaction to mechanical stress in a collagen gel
The reaction of fibroblasts to mechanical forces generated by fibroblasts themselves in anchored collagen lattices was studied. Fibroblasts were cast in collagen gels. Free retracted gels (RG) were compared w...
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Article
Mineralization and Alkaline Phosphatase Activity in Collagen Lattices Populated by Human Osteoblasts
Adult human osteoblastic cells were grown in a native type I collagen gel. Proliferation and viability analyses showed that cells rapidly stopped dividing and became blocked in the G0G1 phase (91% on day 13)....
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Article
Characterization of human osteoblastic cells: Influence of the culture conditions
Human osteoblastic cells were isolated enzymatically from adult human spongy bone and grown in MEM-Ham F12 1:1 medium supplemented with 2% Ultroser (USM). They were subcultured and examined for osteoblast feat...
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Article
Morphological alteration of fibroblasts mechanically stressed in a collagen lattice
The behavior of fibroblast-populated collagen lattices under mechanical stress was studied. Lattice retraction was blocked to allow the application of mechanical stress by contraction of the fibr...
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Article
Chronic liver iron overload in the baboon by ferric nitrilotriacetate
Two baboons receiving intramuscular injections of ferric nitrilotriacetate over a two-year period were compared with two control baboons. The results indicate that in ironoverloaded animals: (1) liver iron exc...