4 Result(s)
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Article
Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence
Cigarette smoking is a leading cause of preventable mortality worldwide. Nicotine dependence, which reduces the likelihood of quitting smoking, is a heritable trait with firmly established associations with se...
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Article
Open AccessGenome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence
We conducted a 1000 Genomes–imputed genome-wide association study (GWAS) meta-analysis for nicotine dependence, defined by the Fagerström Test for Nicotine Dependence in 17 074 ever smokers from five European-...
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Article
Measurement of abdominal fat by CT compared to waist circumference and BMI in explaining the presence of coronary calcium
OBJECTIVE: To evaluate the association between standard and computed tomography (CT)-based measures of obesity and subclinical atherosclerosis, defined as coronary artery calcium (CAC) by Electron Beam Computed T...
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Article
Lipoprotein lipase gene variants and risk of coronary disease: a quantitative analysis of population-based studies
The purpose of this study is to quantify the magnitude of the association between common variants in the lipoprotein lipase gene and coronary disease, based on published population-based studies. Fourteen stud...
